A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES
A subgroup of TRP cation channels named after melastatin protein. They have the TRP domain but lack ANKYRIN repeats. Enzyme domains in the C-terminus leads to them being called chanzymes
A subgroup of TRP cation channels named after the vanilloid receptor. They are very sensitive to TEMPERATURE; hot spicy food, and CAPSAICIN. They contain a TRP domain (a five-turn amphipathic helix with an invariant TRYPTOPHAN) and ANKYRIN repeats. Selectivity for CALCIUM over SODIUM ranges from 3 to 100 fold
Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue
Channing, Mary : BURNED AT THE STAKE : the life and death of mary channing
2017
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Channing, Walter, 1786-1876. : Midwifery and medicine in Boston : Walter Channing, M.D., 1786-1876 / Amalie M. Kass ; [new foreword by Scott Podolsky, M.D.]
2019
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Channing, William Ellery, 1780-1842. : The scholar, the jurist, the artist, the philanthropist : an address before the Phi Beta Kappa Society of Harvard University, at their anniversary, August 27, 1846 / by Charles Sumner
Chanson d'Antioche. : Chanson d'Antioche, chanson de geste : Le Cycle de la Croisade est-il épique?
1980
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Chanson de geste : "Le monde entour et environ" : la geste, la route et le livre dans la littérature médiévale : mélanges offerts à Claude Roussel / études réunies par Émilie Goudeau, Françoise Laurent, Michel Quereuil