A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER
Your entry TRPM Cation Channels would be here
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TRPV Cation Channels -- physiology : Vanilloid Receptor TRPV1 in Drug Discovery : Targeting Pain and Other Pathological Disorders / edited by Arthur Gomtsyan, Connie R. Faltynek
Here are entered works on the presence or absence of individuals registered in schools. Works on the number of individuals registered to attend schools and the demographic characteristics of this population are entered under School enrollment
Trubadurer. : The making of romantic love : longing and sexuality in Europe, South Asia, and Japan, 900-1200 CE / William M. Reddy
2012
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Trubanamen (Qld NW Cape York SD54-15) : Landscape, memory and history : anthropological perspectives / edited by Pamela J. Stewart and Andrew Strathern
Truck accidents -- United States : Frontline. America's dangerous trucks / produced by A. C. Thompson, Gabrielle Schonder, Karim Hajj ; written by A. C. Thompson & Gabrielle Schonder ; directed by Gabrielle Schonder ; a Frontline production with Midnight Films, LLC in partership with ProPublica
