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E-book
Author Gardiner, David M., author.

Title Regenerative engineering and developmental biology : principles and applications / David M. Gardiner
Published Boca Raton : CRC Press, 2017

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Description 1 online resource
Series CRC Press series in regenerative engineering
CRC Press series in regenerative engineering.
Contents Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Acknowledgments -- Editor -- Contributors -- 1: Introduction to regenerative engineering and developmental biology -- SECTION I: SIGNALS ASSOCIATED WITH INJURY THAT INITITATE REGENERATION -- 2: Reactive oxygen species and neuroepithelial interactions during wound healing -- 3: Controlling both the constructive power and the destructive power of inflammation to promote repair and regeneration -- 4: Bioelectrical coordination of cell activity toward anatomical target states: An engineering perspective on regeneration -- 5: The role of nerves in the regulation of regeneration -- 6: Physiological aspects of blastema formation in mice -- SECTION II: HOW CELLS COMMUNICATE TO REMAKE THE PATTERN AND RESTORE FUNCTION -- 7: Retinoic acid and the genetics of positional information -- 8: MicroRNA signaling during regeneration -- 9: Recovering what was lost: Can morphogens scale to enable regeneration? -- 10: Environmental factors contribute to skeletal muscle and spinal cord regeneration -- 11: Engineered flies for regeneration studies -- 12: Positional information in the extracellular matrix: Regulation of pattern formation by heparan sulfate -- 13: Organ shaping by localized signaling centers -- 14: The positional information grid in development and regeneration -- 15: Theorizing about gene expression heterogeneity patterns after cell dedifferentiation and their potential value for regenerative engineering -- SECTION III: INTEGRATION OF NEW STRUCTURES WITH THE OLD -- 16: Directed differentiation of pluripotent stem cells in vitro -- 17: Dedifferentiation as a cell source for organ regeneration -- 18: Epigenetic control of cell fate and behavior -- 19: Developmental plasticity and tissue integration
SECTION IV: PRINCIPLES OF ORGAN DEVELOPMENT AND REGENERATION -- 20: Functional ectodermal organ regeneration based on epithelial and mesenchymal interactions -- 21: Blastema formation in mammalian digit-tip regeneration -- 22: Spinal cord repair and regeneration -- 23: Heart regeneration -- 24: Eye tissue regeneration and engineering -- 25: Skin development and regeneration, and the control of fibrosis -- 26: Programming cells to build tissues with synthetic biology: A new pathway toward engineering development and regeneration -- 27: Recurrent concepts -- Index
Summary "This cutting-edge comprehensive reference work details the technologies related to cell structure in the regeneration of tissue and organs. The focus of the first few chapters is related to what cells do (proliferation, migration, and differentiation/dedifferentiation), leading to the production of a population of regeneration-competent cells. The book then covers the information that tells cells where to go and what to make. This is the regeneration blueprint that tells the cells how to remake patterns and restore functions."--Provided by publisher
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (EBSCO, viewed August 30, 2017)
Subject Tissue engineering -- Methods
Biomedical Engineering -- methods
Tissue Engineering -- methods
Developmental Biology -- methods
Regenerative Medicine -- methods
HEALTH & FITNESS -- Holism.
HEALTH & FITNESS -- Reference.
MEDICAL -- Alternative Medicine.
MEDICAL -- Atlases.
MEDICAL -- Essays.
MEDICAL -- Family & General Practice.
MEDICAL -- Holistic Medicine.
MEDICAL -- Osteopathy.
Tissue engineering
Genre/Form Electronic books
Methods (Music)
Form Electronic book
ISBN 9781351646499
1351646494
9781498723329
1498723322
9781315120188
1315120186