Title Insulin resistance and cancer : epidemiology, cellular and molecular mechanisms and clinical implications / I. George Fantus, editor

Published New York : Springer, ©2011

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Description 1 online resource (xi, 298 pages) : illustrations Series Energy balance and cancer ; 1 Energy balance and cancer ; 1. Contents Insulin and the Physiology of Carbohydrate Metabolism -- Insulin/IGF-1 Signaling Nodes and their Role in Carcinogenesis -- The Mechanisms and Impact of Obesity and Insulin Resistance on Breast Cancer Incidence -- Obesity and Cancer: Epidemiology -- Insulin, Insulin Resistance, and Cancer Associations -- Animal Models of Hyperinsulinemia, Insulin Resistance, and Cancer -- Potential Mechanisms Linking Insulin to Cancer -- Actions of Insulin As a Survival and Growth Factor: Akt, mTOR, and Regulation of Translation -- AMP-Activated Protein Kinase and Cancer Cell Metabolism -- The Role of the IGF Axis in Human Malignancy: Evidence from Epidemiological Studies and Tissue Analysis -- IGF-I and Insulin Receptor Families in Cancer -- Insulin Resistance: Clinical Implications for Cancer Treatment and Prevention Summary A comprehensive book on insulin and cancer Bibliography Includes bibliographical references and index Notes English Subject Cancer. Insulin resistance. Neoplasms -- epidemiology Breast Neoplasms -- epidemiology Breast Neoplasms -- therapy Insulin Resistance Neoplasms -- therapy Obesity -- complications Neoplasms Médecine. Cancer Insulin resistance Form Electronic book Author Fantus, I. George ISBN 9781441999115 1441999116 1283351455 9781283351454 1441999108 9781441999108

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