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Insulin Receptors -- See Receptor, Insulin


A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE
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Insulin -- Receptors. : Molecular basis of insulin action / edited by Michael P. Czech  1985 1
 

Insulin, Regular -- See Insulin


A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1)
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Insulin -- Research -- Periodicals : International journal of experimental diabetes research (Online)    1
 

Insulin resistance -- See Also the narrower term Metabolic syndrome


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Insulin resistance.   25
Insulin resistance -- Animal models : Insulin resistance and insulin resistance syndrome / edited by Barbara Hansen and Eleazar Shafrir  2002 1
Insulin resistance -- Congresses. : The metabolic syndrome : diabetes, obesity, hyperlipidemia & hypertension : proceedings of the 8th European Symposium on Metabolism, held in Padua, Italy, between 2 and 5 October 2002 / editors: Gaetano Crepaldi, Antonio Tiengo, Angelo Avogaro  2003 1
Insulin resistance -- Exercise therapy. : Physical activity and type 2 diabetes : therapeutic effects and mechanisms of action / John A. Hawley, Juleen R. Zierath, editors  2008 1
Insulin resistance -- Handbooks, manuals, etc.   2
Insulin resistance -- Molecular aspecsts : AMPK-S6K1 signaling pathway as a target for treating hepatic insulin resistance / Sang Geon Kim, Il Je Cho, and Hee Yeon Kay  2010 1
Insulin resistance -- Pathophysiology.   3
Insulin resistance -- Pathophysiology -- Congresses.   2
Insulin resistance -- Physiological effect. : TGF-β signalling in human skeletal muscle regeneration and diabetes / Rani Watts  2010 1
Insulin Resistance -- physiology   5
Insulin resistance -- Popular works : A concise summary of Mark Hyman MD's blood sugar solution-- in 30 minutes  2012 1
 

Insulin resistance syndrome -- See Metabolic syndrome


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Insulin Resistance Syndrome X -- See Metabolic Syndrome


A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state
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Insulin-Secreting Cell -- See Insulin-Secreting Cells


A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN
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Insulin-secreting cells -- See Pancreatic beta cells


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Insulin-Secreting Cells   2
Insulin-Secreting Cells -- physiology : BetaSys : systems biology of regulated exocytosis in pancreatic [beta]-cells / Bernhelm Booß-Bavnbek [and others], Editors  2011 1
Insulin-Secreting Cells -- transplantation : Islet transplantation and beta cell replacement therapy / edited by A.M. James Shapiro, James A.M. Shaw  2007 1
Insulin -- Secretion : Congenital hyperinsulinism : a practical guide to diagnosis and management / Diva D. De León-Crutchlow, Charles A. Stanley, editors  2019 1
 

Insulin Sensitivity -- See Insulin Resistance


Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS
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Insulin shock   4
 

Insulin Shock Therapy -- See Convulsive Therapy


Convulsions induced in order to treat MENTAL DISORDERS. It is used primarily in the treatment of severe affective disorders and SCHIZOPHRENIA
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Insulin shock therapy.   4
 

Insulin, Sodium -- See Insulin


A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1)
  1
 

Insulin, Soluble -- See Insulin


A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1)
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Insulin -- Synthesis.   3
Insulin -- Synthesis -- Congresses. : Insulins, growth hormone, and recombinant DNA technology / editor, John L. Gueriguian ; associate editors, Henry I. Miller ... [and others]  1981 1
Insulin -- Therapeuatic use -- Australia : FlexIT- flexible insulin therapy for type 1 diabetes / Matt Cohen ... [and others]  2009 1
Insulin -- therapeutic use   19
Insulin -- Therapeutic use -- Administration. : Oral delivery of insulin / Thundiparambil Azeez Sonia, Chandra P. Sharma  2014 1
Insulin -- Therapeutic use -- Administration -- Periodicals. : Diabetes technology & therapeutics  c1999- 1
Insulin -- Therapeutic use -- Effectiveness. : Insulin deficiency, excess and resistance in human disease / edited by Andrew J. Krentz  2023 1
Insulin -- Therapeutic use -- Handbooks, manuals, etc. : Practical insulin : a handbook for prescribing providers  2007 1
Insulin -- Therapeutic use -- History : Life in the age of insulin : a brief history / Edwin Gale  2023 1
Insulin -- therapeutic use [MESH] : Coping with life on insulin : a guide to insulin-dependent diabetes / Judith M. Steel, Margaret Dunn ; with a foreword by Arnold Bloom  1987 1
Insulin -- Therapeutic use -- Standards. : National standards for the development and quality assessment of services initiating insulin therapy in the ambulatory setting  2004 1
Insulin -- Therapeutic use -- Statistics. : Insulin-treated diabetes in Australia 2000-2007 / [prepared by Katherine Faulks ... [and others]]  2009 1
 

Insulin tolerance -- See Insulin resistance


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Insulinde Euphorbiacées : Antidesma in Malesia and Thailand / by Petra Hoffmann  2005 1
Insuline. : Bittersweet : diabetes, insulin, and the transformation of illness / Chris Feudtner  2003 1
Insuline -- Emploi en thérapeutique -- Administration. : Diabetes mellitus : a fundamental and clinical text / editors, Derek LeRoith, Simeon I. Taylor, Jerrold M. Olefsky  2004 1
Insuline -- Métabolisme.   2
Insuline -- Métabolisme -- Congrès comme sujet. : Molecular and cell biology of type 2 diabetes and its complications / volume editors, F. Belfiore [and others]  1998 1
Insuline -- physiologie. : Diabetes mellitus : a fundamental and clinical text / editors, Derek LeRoith, Simeon I. Taylor, Jerrold M. Olefsky  2004 1
Insuline -- sécrétion. : Molecular and cell biology of type 2 diabetes and its complications / volume editors, F. Belfiore [and others]  1998 1
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