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Book Cover
E-book

Title Insulin Resistance : Childhood Precursors of Adult Disease / Philip S. Zeitler, Kristen J. Nadeau, editors
Edition 2nd ed
Published Cham : Humana Press, ©2020

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Description 1 online resource (352 pages)
Series Contemporary Endocrinology Ser
Contemporary endocrinology (Totowa, N.J.)
Contents Intro; Series Editor Foreword; Reference; Preface to the Second Edition; Contents; Editors; Contributors; Part I: Definition and Epidemiology; 1: Clinical Manifestations of Insulin Resistance in Youth; Introduction; Metabolic Effects of Insulin; Insulin Resistance; Contributory Factors to Developing Insulin Resistance; Non-modifiable Factors; Puberty; Genetics; Epigenetics; Ethnicity; Modifiable Factors; Obesity; Diet and Lifestyle; Physical Activity; Conditions Associated with Insulin Resistance; Metabolic Syndrome; Prediabetes and Type 2 Diabetes; Polycystic Ovary Syndrome (PCOS)
Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH)Lipodystrophies: Inherited and Acquired; Interventional Options; Conclusions; References; 2: Techniques to Assess Insulin Action in Youth; Assessing Insulin Sensitivity; Techniques; Insulin-Glucose Clamp Technique; Hyperinsulinemic-Euglycemic Clamp; Hyperglycemic Clamp; Use of Isotopes and Indirect Calorimetry with the Insulin-Glucose Clamp Technique; The Frequently Sampled Intravenous Glucose Tolerance Test with Minimal Model Analysis; Oral Glucose Tolerance Test
Surrogate Estimates of Insulin Sensitivity and SecretionFasting Estimates of Insulin Sensitivity and Secretion; Estimates of Insulin Sensitivity and Secretion During the Oral Glucose Tolerance Test; Methodologies Not Currently Practiced in Pediatrics; Summary; References; 3: Insulin Resistance in Chronic Disease; Introduction; Asthma; Obesity Can Predate Asthma; Obesity in Persons with Asthma; Asthma and Insulin Resistance; Asthma and the Metabolic Syndrome; Significance and Treatment; Type 1 Diabetes Mellitus; Obesity Predates the Development of Type 1 Diabetes Mellitus
Obesity Among Children and Adolescents with Type 1 Diabetes MellitusInsulin Resistance Among Type 1 Diabetes Mellitus Individuals; Metabolic Syndrome Among Type 1 Diabetes Mellitus Individuals; Significance and Treatment; Cancer Survivors; Components of the Metabolic Syndrome May Be Detected Within the First Years After Hematopoietic Stem Cell Transplantations; Overweight, Obesity, Sarcopenic Obesity, and the Metabolic Syndrome; Factors Associated with Increased Risk of Developing the Metabolic Syndrome; Significance; Psychiatric Disorders; Obesity Predates Psychiatric Disorders
Persons with Psychiatric Disease Are at Higher Risk of Being ObeseThe Metabolic Syndrome in Psychiatric Disorders; Significance and Treatment; Epilepsy; Are Overweight and Obesity More Prevalent in Individuals with Epilepsy?; Insulin Resistance and Epilepsy; Metabolic Syndrome in Epilepsy; Multiple Sclerosis; Classical Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency; Steroids; Other Common Medications Associated with the Metabolic Syndrome; Summary; References; Part II: Pathophysiology; 4: Molecular Mechanisms of Insulin Resistance; Serine Phosphorylation of IRS-1
Notes Print version record
Subject Insulin resistance.
Insulin Resistance
Insulin resistance
Form Electronic book
Author Zeitler, Philip Scott, 1957-
Nadeau, Kristen J.
ISBN 9783030250577
3030250571