| Description |
1 online resource (413 p.) |
| Contents |
Cover -- Title Page -- Copyright Page -- Dedications -- Contents -- Contributors -- Preface -- Acknowledgments -- Chapter 1 Lignins and Lignification: New Developments and Emerging Concepts -- 1.1 Introduction -- 1.2 The Monolignol Pathway and Interacting Pathways - New Lignins -- 1.2.1 Truncated Monolignol Biosynthesis -- 1.2.2 Phenolics from Beyond the Monolignol Biosynthetic Pathway -- 1.2.3 Lignin Design, and the Concept of an Ideal Lignin -- 1.3 Lignin Conjugates, "Clip-Offs' - New Discoveries, and Enhancing Levels -- 1.3.1 Clip-Offs and Their Elevation |
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1.3.2 Exploring Monolignol Conjugates in Compositionally Extreme Lignins -- 1.4 Features of Lignification and the Possibility of New Polymerization Pathways -- 1.4.1 Features of Lignification -- 1.5 The Case for Model Studies and Synthesis -- 1.5.1 The Value of Proper Low-Molecular-Mass Model Compounds -- 1.5.2 Synthetic Lignin Polymers, Dehydrogenation Polymers (DHPs) -- 1.6 New or Improved Analytics -- 1.7 Conclusions and Opportunities -- Acknowledgments -- References -- Chapter 2 Synthesis of Epigallocatechin Gallate, Nobiletin, and Their Derivatives for Chemical-Biological Studies |
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2.1 Synthetic Investigations of Catechin Derivatives -- 2.2 Synthesis and Application of Fluorescent Catechin Probes -- 2.3 Generation of Catechin Antibody -- 2.4 PET Imaging of Biodistribution of Catechin -- 2.5 Practical Synthesis of Nobiletin -- 2.6 Derivatization of Desmethyl Nobiletins -- 2.7 PET Imaging of Biodistribution of Nobiletin -- 2.8 Synthesis and Application of Fluorescent Nobiletin Probe -- 2.9 Conclusions -- References -- Chapter 3 Procyanidins in the Onset and Progression of Colorectal Cancer: Recent Advances and Open Questions -- 3.1 Introduction |
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3.2 Procyanidins: Chemistry and Metabolism -- 3.3 Procyanidins and CRC: Epidemiological Evidence -- 3.4 Procyanidins and CRC: Rodent Studies -- 3.5 Procyanidins and CRC: Mechanisms of Action -- 3.5.1 Interactions with Membranes -- 3.5.2 Inflammation and the NF-B Pathway -- 3.5.3 EGFR and IGF1R Pathways -- 3.6 Conclusions and Open Questions -- Acknowledgments -- Conflict of Interest Disclosure -- References -- Chapter 4 The Potential of Low Molecular Weight (Poly)phenol Metabolites for Attenuating Neuroinflammation and Treatment of Neurodegenerative Diseases |
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4.1 Introduction: Neurodegenerative Disorders, Dietary (Poly)phenols and Neuroinflammation -- 4.2 (Poly)phenols: Metabolism and Distribution -- 4.3 (Poly)phenol Metabolites and Their Brain Permeability -- 4.4 LMW (Poly)phenol Metabolites as Effectors for Attenuating Neuroinflammation -- 4.5 Concluding Remarks -- Acknowledgments -- References -- Chapter 5 Deciphering Complex Natural Mixtures through Metabolome Mining of Mass Spectrometry Data: The Plant Specialized Metabolome as a Case Study -- 5.1 Introduction -- 5.2 Materials and Methods -- 5.2.1 Case Studies -- 5.2.2 Metabolome Mining Tools |
| Notes |
Description based upon print version of record |
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5.2.3 Metabolome Annotation Tools |
| Genre/Form |
Electronic books
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| Form |
Electronic book
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| Author |
Wahala, Kristiina
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de Freitas, Victor
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Quideau, Stéphane
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| ISBN |
9781119844785 |
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1119844789 |
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1119844797 |
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9781119844792 |
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1119844770 |
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9781119844778 |
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