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Book Cover
E-book

Title Antiviral nucleosides : chiral synthesis and chemotherapy / edited by C.K. Chu
Edition 1st ed
Published Amsterdam ; Boston : Elsevier, 2003

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Description 1 online resource (x, 258 pages)
Contents Cover -- Copyright Page -- Preface -- Contents -- Chapter 1. Recent Advances in Antiviral Nucleosides -- 1.1. Introduction -- 1.2. Structural features of nucleosides as antiviral agents -- 1.3. 2'-Deoxy nucleosides and related analogs -- 1.4. 2',3 '-Dideoxy nucleosides and related analog -- 1.5. 2',3 '-Unsaturated nucleosides and related analog -- 1.6. Nucleosides with a heterocyclic sugar ring moiety -- 1.7. 3- or 4-Membered ring nucleosides -- 1.8. Acyclonucleosides -- 1.9. Ribofuranosyl nucleosides -- 1.10. References -- Chapter 2. Chiral Synthesis of Antiviral Nucleosides from Carbohydrate Templates -- 2.1. Introduction -- 2.2. 4'-Thiofuranose nucleosides -- 2.3. Iso- and apio nucleosides -- 2.4. Oxathiolane and dioxolane nucleosides -- 2.5. Cyclopentyl carbocyclic nucleosides -- 2.6. Cyclopropyl carbocyclic nucleosides -- 2.7. C-Nucleosides -- 2.8. Fluorinated nucleosides -- 2.9. Acyclonucleosides -- 2.10. Miscellaneous nucleosides -- 2.11. References -- Chapter 3. Oxathiolane and Dioxolane Nucleosides: Synthesis and Antiviral Activity -- 3.1. Introduction -- 3.2. Oxathiolane nucleosides -- 3.3. Dioxolane nucleosides -- 3.4. References -- Last Page
Summary & bull; Up-to-date review on the chemistry and biology of nucleosides & bull; Modern synthetic methodology & bull; Comprehensive coverage of antiviral nucleosides This book summarizes the recent advances in nucleosides chemistry and chemotherapy over the past 10-15 years. It covers recently discovered nucleoside antiviral agents, their therapeutic aspects and biochemistry, and also extensive reviews on their chiral synthesis
Analysis nucleosiden
nucleosides
virusziekten
viral diseases
antivirale middelen
antiviral agents
farmacologie
pharmacology
geneesmiddelenbehandeling
drug therapy
virussen
viruses
Molecular Biology (General)
Bacteriology
Moleculaire biologie (algemeen)
Bacteriologie
Bibliography Includes bibliographical references
Notes Print version record
Subject Antiviral nucleosides -- Synthesis
Chiral drugs -- Synthesis
Nucleosides -- chemical synthesis
Antiviral Agents -- chemical synthesis
MEDICAL -- Infectious Diseases.
HEALTH & FITNESS -- Diseases -- Contagious.
Chiral drugs -- Synthesis
Form Electronic book
Author Chu, Chung K.
ISBN 9780444513199
0444513191
9781435612631
1435612639
0080524540
9780080524542