| Description |
1 online resource (xvii, 125 pages) : illustrations (some color) |
| Series |
Springer theses, 2190-5061 |
|
Springer theses, 2190-5061
|
| Contents |
1. General introduction -- 2. Metal-responsive DNA strand displacement reactions driven by base pair switching of 5-hydroxyuracil nucleobases -- 3. Metal-dependent base pair switching of N,N,-dicarboxymethyl-5-aminouracil nucleosides -- 4. Metal-responsive DNA tweezers driven by base pair switching of 5-hydroxyuracil nucleobases -- 5. Conclusion and perspectives |
| Summary |
In this thesis, the author proposes "metal-responsive base pair switching" of ligand-modified nucleobases as a novel tool for stimuli-responsive control of DNA assemblies. It is written to demonstrate broad applicability of the base pair switching in dynamic DNA nanotechnology and inspire researchers to use this technique. Based on specific interactions between ligand-type nucleobases and target metal ions, in this volume, DNA hybridization was dynamically controlled through strand displacement reactions. The base pair switching was further applied to develop metal-dependent DNA molecular machines. This novel strategy for stimuli-responsive regulation of DNA assemblies will greatly expand the scope of dynamic DNA nanotechnology. This volume uniquely features importance of elaborate molecular design based on chemistry for imparting stimuli responsiveness to DNA assemblies |
| Notes |
"Doctoral thesis accepted by The University of Tokyo, Tokyo, Japan." |
| Bibliography |
Includes bibliographical references |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed February 7, 2024) |
| Subject |
DNA-ligand interactions.
|
|
Uracil.
|
| Genre/Form |
Electronic books
|
| Form |
Electronic book
|
| ISBN |
9789819994007 |
|
9819994004 |
|
