| Description |
1 online resource (xvii, 349 pages) : illustrations (some color) |
| Contents |
Intro; Preface; Contents; Contributors; I: General Remarks; 1: Epidemiology of Neuroendocrine Tumours: By Site of Tumour and by Geographical Area; 1.1 Introduction; 1.2 Gastroenteropancreatic Neuroendocrine Tumours; 1.2.1 Stomach; 1.2.2 Duodenum; 1.2.3 Small Bowel; 1.2.4 Appendix; 1.2.5 Colon; 1.2.6 Rectum; 1.2.7 Pancreas; 1.3 Thoracic Neuroendocrine Tumours; 1.3.1 Lung; 1.3.2 Thymus; 1.4 Other Sites; 1.4.1 Urinary Tract; 1.4.2 Skin; 1.4.3 Biliary Tract; 1.4.4 Larynx; 1.4.5 Genital Tract; 1.4.6 Liver; 1.4.7 Heart; Bibliography |
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2: Pathological Classification: GEP, TNET, and Rare Forms2.1 Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NEN); 2.1.1 Classification and  Immunohistochemistry; 2.1.2 Grading: Ki67 and  Mitotic Index; 2.1.3 G3 Neuroendocrine Carcinoma (G3-NEC); 2.1.4 Mixed Forms; 2.1.5 Preneoplastic Lesions; 2.2 Thoracic Neuroendocrine Tumors (TNET); 2.2.1 Classification and  Immunohistochemistry; 2.2.2 Grading System; 2.2.3 Preneoplastic Lesions; 2.2.4 Mixed Forms; 2.3 Neuroendocrine Neoplasms in Rare Sites; 2.3.1 Urinary System and  Male Genital Organs; Prostate; Bladder; Kidney; Testis |
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2.3.2 Female Genital OrgansCervix; Endometrium; Ovary and  Fallopian Tubes; Vagina; Vulva; 2.3.3 Breast; 2.3.4 Head and  Neck; Sinonasal Cavities; Larynx; Middle Ear; 2.3.5 Skin; Bibliography; 3: The Molecular Biology of  NET: Current Status and Evaluation of  Biomarkers for Prediction and Prognosis; 3.1 Introduction; 3.2 Genesis, Proliferation, Angiogenesis, and  Metastasis; 3.3 Insights from  Molecular Genetic Analyses; 3.3.1 The Place of  Epigenetics; 3.3.2 The Promise of  Molecular Transcriptomics; 3.4 Conclusion; Bibliography; 4: Tumor Staging TNM; 4.1 Introduction |
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4.2 Neuroendocrine Tumors of  the  Pancreas (PNET)Key Points Pancreas; 4.3 Neuroendocrine Tumors of  the  Stomach; Key Points Stomach; 4.4 Neuroendocrine Tumors of  Duodenum, Jejunum, and  Ileum; Key Points Duodenum, Jejunum, and  Ileum; 4.5 Neuroendocrine Tumors of  the  Appendix Vermiformis; Key Points Appendix; 4.6 Neuroendocrine Tumors of  the  Rectum and  Colon; Key Points Rectum and  Colon; 4.7 Neuroendocrine Tumors of  the  Lung; Key Points Lung; Bibliography; II: Clinical Cases and Their Implications (From Clinical Practice to Guidelines) |
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5: Prognostic Factors: Grading (Ki-67 Index)Clinical Case; 5.1 Comments to the  Case; 5.2 Concluding Remarks; Bibliography; 6: Prognostic Factors: Molecular Pathway â#x80;#x93; Somatostatin Receptors; Clinical Case; 6.1 Comments to the  Case; Bibliography; 7: Prognostic Factors: Molecular Pathway â#x80;#x93; Oncogene (mTOR); Clinical Case; 7.1 Comments to the  Case; Bibliography; 8: Prognostic Factors: Molecular Pathway â#x80;#x93; Tumour Suppressor Gene (MEN1); Clinical Case; 8.1 Comments to the  Case; 8.2 Conclusion; Bibliography |
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9: Prognostic Factors: Nuclear Medicine Imaging (FDG PETâ#x80;#x93;Octreoscan/Gallium PET) |
| Summary |
This book on neuroendocrine tumors (NETs) aims to present, in a clear and innovative manner, a broad topic that is still unevenly and in some respects poorly delineated. The novel feature is the nature of the focus on the principles of prognosis, diagnosis, and therapy, which are outlined on the basis of well-defined clinical scenarios described with the aid of high-quality images and illustrations. The salient observations to emerge from the reported clinical cases are clearly summarized, taking into account evidence from the literature and the available guidelines. All of the significant prognostic factors - histopathological, molecular, and imaging - and current diagnostic and therapeutic strategies for the major NETs (stomach, pancreas, ileum, appendix, bronchus) are covered. In addition, in the introductory part of the book the reader will find information on basic aspects including epidemiology, classification, and underlying biological mechanisms. Neuroendocrine Tumors in Real Life will be of interest to all specialists involved in the management of NETs; it will provide the experienced with important updates and equip trainees and students with a firm understanding of key concepts |
| Notes |
Includes index |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed February 15, 2018) |
| Subject |
Neuroendocrine tumors.
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Neuroendocrine Tumors
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Oncology.
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Endocrinology.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Neuroendocrine tumors
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| Form |
Electronic book
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| Author |
Colao, Annamaria, editor
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Faggiano, Antongiulio, editor
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Herder, Wouter W. de, editor.
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| ISBN |
9783319590240 |
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3319590243 |
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