| Description |
1 online resource (315 pages) |
| Series |
Cancer Metastasis-- Biology and Treatment ; v. 19 |
|
Cancer metastasis (Series) ; v. 19.
|
| Contents |
The Molecular Aspects of Tight Junctions / Elaine A. McSherry, Mark B. Owens, Ann M. Hopkins -- The Distribution of Tight Junctions and Junctional Proteins in the Human Body / Anna-Maria Tokes, Zsuzsa Schaff -- Methods to Study Tight Junctions / Maria Isabel Larre, Catalina Flores-Maldonado, Marcelino Cereijido -- Enhanced Vascular Permeability in Solid Tumors: A Promise for Anticancer Nanomedicine / Sebastien Taurin, Khaled Greish -- Tight junctions, junctional adhesion molecules (JAMs), and the blood brain barrier / Klaus Ebnet, Benjamin F. Brinkmann -- Tight junctions in human urinary bladder cancer / Tracey A. Martin, Mark Haynes, Ninaard Answare -- Tight junctions in colorectal cancer / Frederic Hollande, Marina Papin -- Tight junctions in breast cancer: multifaceted players in tumorigenesis and progression / Yvonne Myal, Anne A.A. Blanchard -- Regulation of tight junctions for therapeutic advantages / Lorenza Gonzalez-Mariscal, Monica Diaz-Coranguez, Miguel Quiros -- VEGF-mediated effects on brain microvascular endothelial tight junctions and transmigration of breast cancer cells across the blood-brain barrier / Shalom Avraham [and others] -- Claudin-g and cancer metastasis / Claudia Malheiros Coutinho-Camillo, Silvia Vanessa Lourenco, Fernando Augusto Soares -- Signalling pathways regulating endothelial cell-cell junctions as a barrier to tumor cell metastasis / Shigetomo Fukuhara, Naoki Mochizuki -- The ROCK signalling pathway and tight junctions / Jane Lane, Tracey A. Martin, Wen G. Jian |
| Summary |
There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Metastasis.
|
|
Neoplasm Metastasis -- physiopathology
|
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Neoplasm Metastasis -- therapy
|
|
Tight Junctions
|
|
Neoplasm Metastasis
|
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MEDICAL -- Oncology.
|
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HEALTH & FITNESS -- Diseases -- Cancer.
|
|
Metastasis
|
| Form |
Electronic book
|
| Author |
Martin, Tracey A
|
|
Jiang, Wen G.
|
| ISBN |
9789400760288 |
|
9400760280 |
|
