| Description |
1 online resource (x, 416 pages) : illustrations (some color) |
| Contents |
Cells and Mediators. Endothelial Cell Origin, Differentiation, Heterogeneity and Function / Anna Grochot-Przęczek, Magdalena Kozakowska, Józef Dulak, Alicja Józkowicz -- Developmental and Pathological Lymphangiogenesis / Angelika Chachaj, Andrzej Szuba -- Vascular-Resident Endothelial Side Population Cells / Hisamichi Naito, Nobuyuki Takakura -- Multiple Roles of Proteases in Angiogenesis / Ester M. Weijers, Victor W.M. van Hinsbergh -- Serpins in Angiogenesis / Czeslaw S. Cierniewski, Joanna Boncela -- Molecular Mechanisms. Endothelial Transcriptional Networks in the Control of Angiogenesis: the ETS Factor / Anna M. Randi -- Insights into Roles of Immediate-Early Genes in Angiogenesis / Leonel Prado-Lourenço, Ahmad M.N. Alhendi, Levon M. Khachigian -- Molecular Mechanisms of Hypoxia-Regulated Angiogenesis / Agnieszka Łoboda, Alicja Józkowicz, Józef Dulak -- MicroRNA Regulation of Angiogenesis / Chandan K. Sen, Yuk Cheung Cyrus Chan -- Nrf2 Transcription Factor and Heme Oxygenase-1 as Modulators of Vascular Injury and Angiogenesis / Urszula Florczyk, Alicja Józkowicz, Józef Dulak -- Metabolism of Methylarginines and Angiogenesis / Hilda Tsang, Lucio Iannone, Beata Wojciak-Stothard -- The Vasohibin Family: Novel Regulators of Angiogenesis / Yasufumi Sato -- Diseases and Therapy. Hypoxia-Induced Pathological Angiogenesis in Zebrafish / Lasse D. Jensen, Pegah Rouhi, Yihai Cao -- Tumor Angiogenesis: Fishing for Screening Models / Dafne Gays, Vera Mugoni, Massimo M. Santoro -- Vascular Complications in Diabetes / Louise L. Dunn, Kim Hoe Chan, Martin K.C. Ng, Roland Stocker -- Angiogenesis in Rheumatoid Arthritis / Sofia Konisti, Serafim Kiriakidis, Ewa M. Paleolog -- Angiogenic Signaling and Structural Abnormalities in Tumors / Magdalena Tertil, Klaudia Skrzypek, Agnieszka Łoboda -- Endothelium in Pathologic Angiogenesis and Angiogenesis-Mediated Therapies / Maria Paprocka, Catherine Grillon, Danuta Duś, Claudine Kieda |
| Summary |
The book presents the overview of the current knowledge in some fields of vascular biology, addressing cellular and molecular aspects of blood-vessel formation and their role in health and disease. The major factors involved in the formation of blood vessels are presented by scientists actively involved in this area of research. Special emphasis is put on the presentation of various molecular mechanisms not addressed in similar works to date. The book is divided into three parts. The first part describes the cells and mediators in angiogenesis. The significance of various populations of potential endothelial progenitors is particularly highlighted. The chapters of the second part focus on molecular mechanisms, with special emphasis on the role of hypoxia, gasotransmitters and reactive oxygen species as well as microRNAs in regulation of angiogenic processes. In the third part, the pathological aspects of disturbed - aggravated or impaired - vascularization are discussed and new modalities for potential therapies are presented. The book is intended for scientists and PhD students in the fields of vascular biology and cancer research. It may be of interest for medical professionals in the fields of cardiovascular disease, diabetes, oncology and rheumatoid arthritis |
| Analysis |
celbiologie |
|
cellular biology |
|
biomedische wetenschappen |
|
biomedicine |
|
immunologie |
|
immunology |
|
neoplasms |
|
oncologie |
|
oncology |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Notes |
Includes index |
|
Online resource; title from PDF title page (SpringerLink, viewed February 17, 2014) |
| Subject |
Neovascularization.
|
|
Neovascularization, Physiologic
|
|
Neovascularization, Pathologic
|
|
Neovascularization
|
| Form |
Electronic book
|
| Author |
Dulak, Józef, editor
|
|
Józkowicz, Alicja, editor
|
|
Łoboda, Agnieszka, editor
|
| ISBN |
9783709114285 |
|
3709114284 |
|
3709114276 |
|
9783709114278 |
|
