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Title Arachidonate related lipid mediators / edited by Robert C. Murphy, Frank A. Fitzpatrick
Published San Diego : Academic Press, [1990]
©1990
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Description 1 online resource (xxxviii, 683 pages) : illustrations
Series Methods in enzymology ; v. 187
Methods in enzymology ; v. 187
Contents Nomenclature / William L. Smith [and others] -- Electron-capture negative-ion chemical ionization mass spectrometry of lipid mediators / Ian A. Blair, Robert C. Murphy and Frank A. Fitzpatrick -- Enzyme immunoassays of eicosanoids using acetylcholinesterase / Philippe Pradelles [and others] -- Radioimmunoassay of 11-dehydrothromboxane B2 / Giovanni Ciabattoni [and others] -- Measurement of thromboxane metabolites by gas chromatography-mass spectrometry / Francesca Catella [and others] -- Quantification of 9[alpha],11[beta]-prostaglandin F2 by stable isotope dilution mass spectrometric assay / Daniel F. Wendelborn [and others] -- Immunoaffinity purification-chromatographic quantitative analysis of arachidonic acid metabolites / J. James Vrbanac [and others] -- Preparation of tetradeuterated leukotriene A4 methyl ester: methyl-[11,12,14,15-2H4]-(5S, 6S)-Oxido-(7E,9E,11Z,14Z)-eicosatetraenoate / J.P. Lellouche [and others] -- Quantitative gas chromatography-mass spectrometry analysis of leukotriene B4 / W. Rodney Mathews, Robert C. Murphy and Frank A. Fitzpatrick -- Enzyme immunoassays for leukotrienes C4 and E4 using acetylcholinesterase / Philippe Pradelles [and others] -- Quantitation of sulfidopeptide leukotrienes in biological fluids by gas chromatography-mass spectrometry / Robert C. Murphy [and others] -- Automated on-line extraction and profiling of lipoxygenase products of arachidonic acid by high-performance liquid chromatography / Pierre Borgeat [and others] -- Preparation of antibodies directed against leukotrienes / Edward C. Hayes, Robert C. Murphy and Frank A. Fitzpatrick -- Bioassay of paf-acether by rabbit platelet aggregation / Marie-Jeanne Bossant [and others] -- Bioassay of platelet-activating factor by release of [3H]serotonin / Peter M. Henson, Robert C. Murphy and Frank A. Fitzpatrick -- Quantitation of platelet-activating factor by gas chromatography-mass spectrometry / Keith L. Clay, Robert C. Murphy and Frank A. Fitzpatrick -- Quantitative analysis of platelet-activating factor by gas chromatography-negative-ion chemical ionization mass spectrometry / Walter C. Pickett [and others] -- Isolation of platelet-activating factor and purification by thin-layer chromatography / Donald J. Hanahan, Robert C. Murphy and Frank A. Fitzpatrick
Separation and characterization of arachidonate-containing phosphoglycerides / Floyd H. Chilton, Robert C. Murphy and Frank A. Fitzpatrick -- High-performance liquid chromatography separation and determination of lipoxins / Charles N. Serhan, Robert C. Murphy and Frank A. Fitzpatrick -- Quantitation of epoxy- and dihydroxyeicosatrienoic acids by stable isotope-dilution mass spectrometry / John Turkw [and others] -- High-performance liquid chromatography for chiral analysis of eicosanoids / Alan R. Brash [and others] -- Extraction of phospholipids and analysis of phospholipid molecular species / George M. Patton [and others] -- Macrophage phospholipase A2 specific for sn-2-arachidonic acid / Christina C. Leslie, Robert C. Murphy and Frank A. Fitzpatrick -- Measurement of phosphoinositide-specific phospholipase c activity / John E. Bleasdale [and others] -- Solubilization of arachidonate-CoA ligase from cell membranes, chromatographic separation from nonspecific long-chain fatty acid CoA ligase, and isolation of mutant cell line defective in arachidonate-CoA ligase / Michael Laposata, Robert C. Murphy and Frank A. Fitzpatrick -- Preparation of prostaglandin H2: Extended purification/analysis scheme / Duane Venton [and others] -- Purification and properties of pregnancy-inducible rabbit lung cytochrome P-450 prostaglandin [omega]-hydroxylase / A. Scott Muerhoff [and others] -- Purification of arachidonate 5-lipoxygenase from potato tubers / Pallu Reddanna [and others] -- Leukotriene metabolism by isolated rat hepatocytes / Michael A. Shirley [and others] -- Purification and characterization of human lung leukotriene A4 hydrolase / Nobuya Ohishi [and others] -- Potato arachidonate 5-lipoxygenase: Purification, characterization, and preparation of 5(S)-hydroperoxyeicosatetraenoic acid / Takao Shimizu [and others] -- Leukotriene C4 synthase: Characterization in mouse mastocytoma cells / Mats Söderström [and others] -- Leukocyte arachidonate 5-lipoxygenase: Isolation and characterization / Carol A. Rouzer [and others] -- 1 Cytochrome P-450LTB and inactivation of leukotriene B4 / Roy J. Soberman, Robert C. Murphy and Frank A. Fitzpatrick -- Cytosolic liver Enzymes catalyzing hydrolysis of leukotriene A4 to leukotriene B4 and 5,6-dihydroxyeicosatetraenoic acid / Jesper Z. Haeggström, Robert C. Murphy and Frank A. Fitzpatrick -- Purification and properties of leukotriene C4 synthase from guinea pig lung microsomes / Roy J. Soberman, Robert C. Murphy and Frank A. Fitzpatrick -- 1 Immunoaffinity purification of arachidonate 5-Lipoxygenase from porcine leukocytes / Natsuo Ueda [and others] -- Platelet-activating factor acetylhydrolase from human plasma / Diana M. Stafforini [and others] -- Synthesis of epoxyeicosatrienoic acids and heteroatom analogs / J.R. Falck [and others] -- Isolation of rabbit renomedullary cells and arachidonate metabolism / Mairead A. Arroll [and others] -- Ocular cytochrome P-450 metabolism of arachidonate: Synthesis and bioassay / Michal Laniado Schwartzman [and others] -- Cytochrome P-450 arachidonate oxygenase / Jorge H. Capdevila [and others] -- Radioligand binding assays for thromboxane A2/prostaglandin H2 receptors / Perry V. Halushka [and others] -- Thromboxane A2/prostaglandin H2 receptor antagonists / Guy C. Le Breton [and others] -- Assessment of leukotriene D4 receptor antagonists / David Aharony, Robert C. Murphy and Frank A. Fitzpatrick -- Sulfidopeptide leukotriene receptor binding assays / Seymour Mong, Robert C. Murphy and Frank A. Fitzpatrick
Ginkgolides and platelet-activating factor binding sites / D.J. Hosford [and others] -- Kadsurenone and other related lignans as antagonists of platelet-activating factor receptor / T.Y. Shen [and others] -- Use of WEB 2086 and WEB 2170 as platelet-activating factor antagonists/at] / Jorge Casals-Stenzel [and others] -- Cloning of sheep and mouse prostaglandin endoperoxide synthases / David L. Dewitt [and others] -- Preparation and proteolytic cleavage of apoprostaglandin endoperoxide synthase / Rebecca Odenwaller [and others] -- Cloning of leukotriene A4 hydrolase cDNA / Olof Rådmark [and others] -- Molecular biology and cloning of archidonate 5-lipoxygenase / Colin D. Funk [and others] -- Parietal cell preparation and arachidonate metabolism / N. Ann Payne [and others] -- Culture of bone marrow-derived mast cells: A model for studying oxidative metabolism of arachidonic acid and synthesis of other molecules derived from membrane phospholipids / Ehud Razin, Robert C. Murphy and Frank A. Fitzpatrick -- Endothelial cells for studies of platelet-activating factor and arachidonate metabolites / Guy A. Zimmerman [and others] -- Use of cultured cells to study arachidonic acid metabolism / Robert R. Gorman [and others] -- Eicosanoid biochemistry in cultured glomerular mesangial cells / Michael S. Simonson [and others] -- Leukotriene B4 biosynthesis by erythrocyte-neutrophil interactions / David A. Jones [and others] -- Leukotriene C4 biosynthesis during polymorphonuclear leukocyte-vascular cell interactions / Steven J. Feinmark, Robert C. Murphy and Frank A. Fitzpatrick -- Release and metabolism of leukotriene A4 in neutrophil-mast cell interactions / Clemens A. Dahinden [and others] -- Interaction between platelets and lymphocytes in biosynthesis of prostacyclin / Kenneth K. Wu [and others] -- Eicosanoid interactions between platelets, endothelial cells, and neutrophils / Aaron J. Marcus, Robert C. Murphy and Frank A. Fitzpatrick -- Isolated perfused rat lung in arachidonate studies / Shih-Wen Chang [and others] -- Isolated coronary-perfused mammalian heart: Assessment of eicosanoid and platelet-activating factor release and effects / Roberto Levi [and others] -- Preparation of human and animal lung tissue for eicosanoid research / T. Viganò [and others]
Summary This volume includes information on arachidonic acid metabolites and platelet activating factor. Assays for the quantitative measurement of prostaglandins, leukotrienes, and platelet-activating factor, including enzyme immunoassays and mass spectrophotometric techniques, are presented. Preparation and analysis of cytochrome P-450 metabolites of arachidonic acid are discussed. The isolation, purification, and assay of enzymes important in the biosynthesis and metabolism of these lipids are included
Analysis Lipids
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Eicosanoic acid.
Prostaglandins.
Leukotrienes.
Platelet activating factor.
Arachidonic Acids.
Lipid Metabolism.
Form Electronic book
Author Murphy, Robert C.
Fitzpatrick, Frank A.
ISBN 0121820882 (electronic bk.)
9780121820886 (electronic bk.)