Description |
1 online resource (579 p.) |
Series |
Series in Cellular and Clinical Imaging Ser |
|
Series in Cellular and Clinical Imaging Ser
|
Contents |
Cover -- Half Title -- Series Page -- Title Page -- Copyright Page -- Table of Contents -- Preface -- Editors -- Contributors -- Part I Function and Structural Neurophotonic Imaging -- Chapter 1 Miniaturized Optical Neuroimaging Systems -- 1.1 Introduction -- 1.2 Design Criteria for Miniaturized Optical Neuroimaging Devices -- 1.2.1 Fiber Optic-Adapted Systems versus Discrete Systems -- 1.3 Applications of Miniaturized Optical Neuroimaging Devices -- 1.3.1 Miniaturized Single-Photon Fluorescence Microscopes -- 1.3.2 Miniaturized Intrinsic Contrast Microscopes |
|
1.3.3 Miniaturized Two-Photon Fluorescence Microscopes -- 1.4 Challenges of Miniaturized Neuroimaging Systems -- 1.4.1 Miniaturized Microscope Weight Constraints -- 1.4.2 Motion Artifacts -- 1.4.3 Interpretation of Animal Behaviors -- 1.4.4 Fiber Optic-Adapted versus Discrete Systems -- 1.5 Future Directions -- 1.5.1 Optogenetic Control of Neural Circuits -- 1.5.2 Novel Imaging Applications -- 1.5.3 Towards a True Tetherless Imaging System? -- References -- Chapter 2 Functional Imaging with Light-Sheet Microscopy -- 2.1 Introduction -- 2.2 Principles of Light-Sheet Microscopy |
|
2.2.1 Live-Imaging of Multi-Cellular Organisms -- 2.2.2 Imaging at High Spatiotemporal Resolution -- 2.3 Functional Imaging of the Nervous System using Light-Sheet Microscopy -- 2.3.1 Light-Sheet Functional Imaging in Zebrafish -- 2.3.2 Light-Sheet Functional Imaging in Drosophila -- 2.3.3 Light-Sheet Functional Imaging in Mammalian Brains -- 2.4 Performance and Design Choices -- 2.4.1 Temporal Resolution -- 2.4.2 Spatial Resolution -- 2.4.3 Mode of Fluorescence Excitation and Imaging Geometry -- 2.5 Processing and Analysis of Light-Sheet Functional Imaging Data -- 2.6 Outlook -- References |
|
Chapter 3 Two-Photon Microscopy in the Mammalian Brain -- 3.1 Functional Two-Photon Laser-Scanning Microscopy -- 3.2 Rapid Serial Lateral Scanning for Functional TPLSM -- 3.2.1 Rapid Mechanical Scanning -- 3.2.2 Rapid Inertia-Free Scanning -- 3.3 Beam Propagation inside a Scattering Medium -- 3.4 Parallel Acquisition for Rapid Functional Two-Photon Microscopy -- 3.4.1 Multifocal Multiphoton Microscopy -- 3.4.2 Temporal Focusing Multiphoton Microscopy -- 3.4.3 Light Sheet Microscopy -- 3.5 Rapid Axial Scanning for Volumetric Functional Imaging |
|
3.5.1 Rapid Mechanical Scanning of the Objective Lens -- 3.5.2 Remote Scanning of the Focal Spot -- 3.5.2.1 Remote Scanning by Lens Tuning -- 3.5.2.2 Remote Scanning by a Moving Mirror -- References -- Chapter 4 Light Field Microscopy for In Vivo Ca2+ Imaging -- 4.1 Introduction -- 4.2 Principles of LFM -- 4.2.1 Basic Principles -- 4.2.2 Performance and Design Trade-Offs -- 4.2.3 Recovering Volumetric Data -- 4.3 Experimental Aspects -- 4.3.1 Optomechanical Setup -- 4.3.2 Alignment Strategy -- 4.4 Application of LFM to Ca2+ Imaging -- 4.4.1 Light-field Imaging of Neural Activity In Vivo |
Notes |
Description based upon print version of record |
|
4.4.2 Seeded Iterative Demixing |
Form |
Electronic book
|
Author |
Shoham, Shy
|
ISBN |
9781498718769 |
|
1498718760 |
|