| Description |
1 online resource |
| Contents |
Introduction to biomanufacturing / Mark F. Witcher -- Product-process-facility relationship / Jeffery Odum -- Regulatory considerations of biomanufacturing facilities / Kip Priesmeyer -- Biopharmaceutical facility design and validation / Jeffery Odum -- Closed systems in bioprocessing / Jeffery Odum -- Aseptic manufacturing considerations for biomanufacturing facility design / Jeffery Odum, Hartmut Schaz, and Larry Pressley -- Facility control of microorganisms : containment and contamination / Jonathan Crane -- Process-based laboratory design / Henriette Schubert and Flemming K. Nielsen -- Case study : pharmaceutical pilot plant design and operation / Beth H. Junker -- Addressing sustainability in biomanufacturing facility design / Josh Capparella, Samuel Colucci, Daniel Conner, Robert Dick, and Amanda Weko -- Technology's impact on the biomanufacturing facility of the future / Jeffery Odum and Mark F. Witcher |
| Summary |
Essential information for architects, designers, engineers, equipment suppliers, and other professionals who are working in or entering the biopharmaceutical manufacturing field Biomanufacturing facilities that are designed and built today are radically different than in the past. The vital information and knowledge needed to design and construct these increasingly sophisticated biopharmaceutical manufacturing facilities is difficult to find in published literature-and it's rarely taught in architecture or design schools. This is the first book for architects and designers that fills this void. Process Architecture in Biomanufacturing Facility Design provides information on design principles of biopharmaceutical manufacturing facilities that support emerging innovative processes and technologies, use state-of-the-art equipment, are energy efficient and sustainable, and meet regulatory requirements. Relying on their many years of hands-on design and operations experience, the authors emphasize concepts and practical approaches toward design, construction, and operation of biomanufacturing facilities, including product-process-facility relationships, closed systems and single use equipment, aseptic manufacturing considerations, design of biocontainment facility and process based laboratory, and sustainability considerations, as well as an outlook on the facility of the future.-Provides guidelines for meeting licensing and regulatory requirements for biomanufacturing facilities in the U.S.A and WHO-especially in emerging global markets in India, China, Latin America, and the Asia/Pacific regions -Focuses on innovative design and equipment, to speed construction and time to market, increase energy efficiency, and reduce footprint, construction and operational costs, as well as the financial risks associated with construction of a new facility prior to the approval of the manufactured products by regulatory agencies -Includes many diagrams that clarify the design approach Process Architecture in Biomanufacturing Facility Design is an ideal text for professionals involved in the design of facilities for manufacturing of biopharmaceuticals and vaccines, biotechnology, and life-science industry, including architects and designers of industrial facilities, construction, equipment vendors, and mechanical engineers. It is also recommended for university instructors, advanced undergraduates, and graduate students in architecture, industrial engineering, mechanical engineering, industrial design, and industrial interior design |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record and CIP data provided by publisher |
| Subject |
Factories -- Design and construction.
|
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Pharmaceutical biotechnology industry.
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Manufacturing and Industrial Facilities
|
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SCIENCE -- Chemistry -- Industrial & Technical.
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TECHNOLOGY & ENGINEERING -- Chemical & Biochemical.
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Factories -- Design and construction
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Pharmaceutical biotechnology industry
|
| Form |
Electronic book
|
| Author |
Odum, Jeffery N., editor
|
|
Flickinger, Michael C., editor.
|
| LC no. |
2017054232 |
| ISBN |
9781118833650 |
|
1118833651 |
|
9781119369172 |
|
1119369177 |
|
1118833678 |
|
9781118833674 |
|
