1. Introduction / Elizabeth A. Eisenhauer -- 2. Preclinical data and requirements / Elizabeth A. Eisenhauer -- 3. Basics of phase I design : first-in-man studies / Elizabeth A. Eisenhauer -- 4. Ethical issues in phase I cancer trials / Elizabeth A. Eisenhauer -- 5. Special populations and interaction studies / Chris Twelves -- 6. Statistical designs for first-in-man phase I cancer trials / Marc Buyse -- 7. Writing the protocol / Elizabeth A. Eisenhauer -- 8. Before you begin / Elizabeth A. Eisenhauer -- 9. Practical aspects of pharmacokinetics and pharmacodynamics / Chris Twelves -- 10. Running the study / Elizabeth A. Eisenhauer -- 11. Reporting and interpreting results / Elizabeth A. Eisenhauer
Bibliography
Includes bibliographical references (pages [282]-286) and index
