Title Studies on men's health and fertility / Ashok Agarwal, R. John Aitken, Juan G. Alvarez, editors

Published New York : Humana Press, ©2012

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Description 1 online resource (xvi, 671 pages) : color portraits Series Oxidative stress in applied basic research and clinical practice Oxidative stress in applied basic research and clinical practice. Contents Electromagnetic Radiation and Oxidative Stress in the Male Germ Line / Geoffry N. De Iuliis, Bruce V. King and R. John Aitken -- Mitochondria as a Source of ROS in Mammalian Spermatozoa / Adam John Koppers -- Cryostorage and Oxidative Stress in Mammalian Spermatozoa / Stuart A. Meyers -- Sperm Capacitation as an Oxidative Event / Eve de Lamirande and Cristian O'Flaherty -- Protection of Epididymal Spermatozoa from Oxidative Stress / Joël R. Drevet -- Lipid Peroxidation in Human Spermatozoa / Juan G. Alvarez and R. John Aitken -- Age and Oxidative Stress in the Germ Line / Bernard Robaire, Catriona Paul and Johanna Selvaratnam -- Heat and Oxidative Stress in the Germ Line / Koji Shiraishi -- Cytokines and Oxidative Stress in the Germ Line / Monika Fraczek, Anna Czernikiewicz and Maciej Kurpisz -- Metabolic Strategy in Mammalian Spermatozoa and Oxidative Stress / Juan G. Alvarez -- Role of Protamine Disulphide Cross-Linking in Counteracting Oxidative Damage to DNA / Juan G. Alvarez and Jaime Gosalvez -- Role of Caspase, PARP, and Oxidative Stress in Male Infertility / Tamer M. Said and Fariba Khosravi -- Methods for the Detection of ROS in Human Sperm Samples / David Benjamin, Rakesh K. Sharma, Arozia Moazzam and Ashok Agarwal -- Direct Methods for the Detection of Reactive Oxygen Species in Human Semen Samples / R. John Aitken, Geoffry N. De Iuliis and Mark A. Baker -- ROS and Semen Quality / Ralf Henkel -- Oxidative Stress and Male Infertility: A Clinical Perspective / Kelton Tremellen Oxidative Stress and Testicular Torsion / Dikmen Dokmeci -- Varicocele and Oxidative Stress / Armand Zini and Naif Al-hathal -- Recreational Drugs and ROS Production in Mammalian Spermatozoa / Fábio Firmbach Pasqualotto and Eleonora Bedin Pasqualotto -- Oxidative Stress, DNA Damage, and Apoptosis in Male Infertility / Tamer M. Said, Constanze Fischer-Hammadeh, Mohammed Hamad, Khaled Refaat and Mohamad Eid Hammadeh -- Effect of Oxidative Stress on ART Outcome / Mohamad Eid Hammadeh, Mohammed Hamad, Khaled Refaat, Tamer M. Said and Constanze Fischer-Hammadeh -- Oxidative Stress and the Use of Antioxidants for Idiopathic OATs / Ashok Agarwal, Anthony H. Kashou and Lucky H. Sekhon -- Leukocytospermia and Oxidative Stress / Margot Flint, Ashok Agarwal and Stefan S. du Plessis -- Clinical Consequences of Oxidative Stress in Male Infertility / Tamer M. Said, Sheila R. Gokul and Ashok Agarwal -- Oxidative Stress and Infection / Enzo Vicari, Sandro La Vignera and Aldo E. Calogero -- The Role of Obesity in ROS Generation and Male Infertility / Anthony H. Kashou, Stefan S. du Plessis and Ashok Agarwal -- Oxidative Stress in Benign Prostate Hyperplasia / Murat Savas -- Role of Oxidative Stress in ED: Unraveling the Molecular Mechanism / Biljana Musicki and Arthur L. Burnett Summary Studies on Men's Health and Fertility provides a comprehensive series of up-to-the-minute reviews addressing the role of oxidative stress in the aetiology of reproductive pathologies in the male. This volume represents by far the most detailed, authoritative review of the field that has been produced to date.¡ The text encompasses the basic science of reactive oxygen species (ROS) production by mammalian spermatozoa, the way in which these highly reactive molecules are processed by the germ line and the physiological significance of this redox activity in the generation of a functional gamete. The factors responsible for perturbing the delicate balance between physiological redox signaling on the one hand and oxidative stress on the other are also extensively reviewed and some of the first clues concerning the underlying mechanisms (age, heat, infection, cryostorage, aberrant lipid metabolism), clearly identified.¡ From a clinical perspective there are chapters setting out the methods we should be using to diagnose oxidative stress in the male germ line, a clinical perspective on the aetiology of this condition and detailed considerations of the most suitable means of ameliorating such stress from a therapeutic point of view.¡ Studies on Men's Health and Fertility is intended to provide clinicians and scientists with a snap shot of the current status of this exciting, rapidly moving field. The book will be of value to clinicians interested in strategies for the management of oxidative stress in their infertility patients and scientists wishing to understand the molecular mechanisms underpinning the generation of ROS by these cells and its pathophysiological significance.¡ It was not so long ago that the ability of spermatozoa to generate ROS was a hotly disputed topic.¡ With the publication of this book such doubts can finally be laid to rest. There is now no doubt that these cells actively generate ROS, that oxidative stress is a major contributor to defects in male reproductive health and that the successful clinical management of this condition depends on developing a deeper understanding of the underlying molecular mechanisms.¡ In this quest, Studies on Men's Health and Fertility will be seen as a clear and important milestone Analysis Life sciences Reproductive Medicine Cytology Oxidative Stress Cell Biology voortplantingsorganen reproductive organs geneeskunde medicine celbiologie cellular biology Human Physiology and Anatomy Humane fysiologie en anatomie Bibliography Includes bibliographical references and index Notes English Subject Oxidative stress. Generative organs, Male -- Diseases. Fertility, Human. Health. Infertility. Metabolism. Genitourinary organs -- Diseases. Medical care. Diseases. Fertility. Infertility, Male. Health Reproductive Physiological Phenomena Infertility Metabolism Stress, Physiological Reproductive and Urinary Physiological Phenomena Population Characteristics Genital Diseases, Male Physiological Phenomena Male Urogenital Diseases Phenomena and Processes Delivery of Health Care Disease Oxidative Stress Fertility Men's Health Infertility, Male Patient Care health. metabolism (biological concept) MEDICAL -- Endocrinology & Metabolism. MEDICAL -- Nutrition. Metabolism Medical care Infertility, Male Infertility Health Genitourinary organs -- Diseases Fertility Diseases Fertility, Human Generative organs, Male -- Diseases Oxidative stress Form Electronic book Author Agarwal, Ashok (Physician) Aitken, R. J. Alvarez, Juan G ISBN 9781617797767 1617797766 1617797758 9781617797750 1627038981 9781627038980

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