| Description |
1 online resource (viii, 327 pages) : illustrations |
| Contents |
Old Players -- Hydrogen Peroxide: The Good, The Bad, and The Ugly -- Peroxynitrite: A Key Molecule in Skin Tissue Response to Different Types of Stress -- Cellular and Environmental Electrophiles: Balancing Redox Signaling, Inflammation, and Cell Death Pathways -- The Role of Reactive Nitrogen Species (RNS) in the Activation of Nuclear Factor Kappa B (NFkB) and Its Implications for Biological Systems: The Question of Balance -- Neutrophil-Derived Oxidants as Modulators of Polyunsaturated Fatty Acid Metabolism -- Fatty Acids in the Modulation of Reactive Oxygen Species Balance in Cancer -- The Question of Balance: The Interaction Between Blood and Ozone -- Iron and Erythrocytes: Physiological and Pathophysiological Aspects -- The Adventures of Superoxide Dismutase in Health and Disease: Superoxide in the Balance -- Glutathione Metabolism: Favorable Versus Unfavorable Effects -- Dual Roles of Oxidative Stress in the Lungs -- Antioxidants: How They Work -- New Players -- The Role of DUOX Isozymes in the Respiratory Tract Epithelium -- Hypertension, Diabetes, Oxidative Stress, and Cardiovascular Remodeling: Making the Connection with p66shc -- A Role of BRCA1-Associated Protein BARD1 in Oxidative Stress Response and Signaling and Proliferation Control -- Postprandial Events as a Trigger for Redox Unbalance: Role of Dietary Lipid Hydroperoxides and Antioxidants -- F2-Isoprostanes: Markers and Mediators of an Imbalanced Redox Status in the Liver |
| Summary |
Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathoge |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Oxidation, Physiological.
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Oxidation-reduction reaction.
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Oxidative Stress -- physiology
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Antioxidants -- metabolism
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Free Radicals -- metabolism
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Oxidation-Reduction
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MEDICAL -- Pathology.
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MEDICAL -- Pathophysiology.
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Biomédecine.
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Sciences de la vie.
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Oxidation-reduction reaction
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Oxidation, Physiological
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| Form |
Electronic book
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| Author |
Valacchi, Giuseppe.
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Davis, Paul A., Dr.
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| ISBN |
9781402083990 |
|
1402083998 |
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9781402083983 |
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140208398X |
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1281492256 |
|
9781281492258 |
|
