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Title Methods in systems biology / edited by Daniel Jameson, Malkhey Verma, and Hans V. Westerhoff
Edition First edition
Published London : Academic, 2011
Online access available from:
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Description 1 online resource (liv, 715 pages, 4 unnumbered pages of plates) : illustrations (some color)
Series Methods in enzymology ; v. 500
Methods in enzymology ; v. 500
Contents section 1. [untitled]. Systems biology left and right / Hans V. Westerhoff -- section 2. Machines for systems biology. Mass spectrometry in systems biology : an introduction / Warwick B. Dunn ; High-throughput quantification of posttranslational modifications in situ by CA-FILM / Hernán E. Grecco ... [et al.] ; Absorption spectroscopy / Sanjay M. Nilapwar ... [et al.] -- section 3. Nucleic acids and systems biology. A strand-specific library preparation protocol for RNA sequencing / Tatiana Borodina, James Adjaye, and Marc Sultan ; Quantitative real-time PCR-based analysis of gene expression / J. Jozefczuk and James Adjaye -- section 4. Protein production and quantification for systems biology. Quantification of proteins and their modifications using QconCAT technology / Kathleen M. Carroll, Francesco Lanucara, and Claire E. Eyers ; Mass spectrometric-based quantitative proteomics using SILAC / Francesco Lanucara and Claire E. Eyers ; Nucleic acid programmable protein array : a just-in-time multiplexed protein expression and purification platform / Ji Qiu and Joshua LaBaer ; Systems biology of recombinant protein production using Bacillus megaterium / Rebekka Biedendieck ... [et al.] ; Protein production in Saccharomyces cerevisiae for systems biology studies / Naglis Malys ... [et al.] -- section 5. Enzymatic assays in systems biology research. Towards a full quantitative description of yeast metabolism : a systematic approach for estimating the kinetic parameters of isoenzymes under In vivo like conditions / Hanan L. Messiha, Naglis Malys, and Kathleen M. Carroll ; Enzyme kinetics for systems biology : when, why and how / Malgorzata Adamczyk ... [et al.] -- section 6. Sample preparation in metabolic studies. The use of continuous culture in systems biology investigations / Catherine L. Winder and Karin Lanthaler ; Sample preparation related to the intracellular metabolome of yeast : methods for quenching, extraction, and metabolite quantitation / Warwick B. Dunn and Catherine L. Winder ; Plant metabolomics and its potential for systems biology research : background concepts, technology, and methodology / J. William Allwood ... [et al.] ; The study of mammalian metabolism through NMR-based metabolomics / Reza Salek, Kian-Kai Cheng, and Julian Griffin -- section 7. Mathematical modelling in systems biology. Building a kinetic model of trehalose biosynthesis in Saccharomyces cerevisiae / Kieran Smallbone ... [et al.] ; Sustainable model building : the role of standards and biological semantics / Falko Krause ... [et al.] ; From reaction networks to information flow : using modular response analysis to track information in signaling networks / Pascal Schulthess and Nils Blüthgen ; Whole-genome metabolic network reconstruction and constraint-based modeling / Charles R. Haggart ... [et al.] -- section 8. Understanding systems biology. Hands-on metabolism : analysis of complex biochemical networks using elementary flux modes / Sascha Schäuble, Stefan Schuster, and Christoph Kaleta ; How to obtain true and accurate rate-values / Sef J. Heijnen, and Peter J.T. Verheijen ; A practical guide to genome-scale metabolic models and their analysis / Filipe Santos, Joost Boele, and Bas Teusink ; Supply-demand analysis : a framework for exploring the regulatory design of metabolism / Jan-Hendrik S. Hofmeyr and Johann M. Rohwer ; Modular kinetic analysis / Klaas Krab ; Quantitative analysis of flux regulation through hierarchical regulation analysis / Karen van Eunen ... [et al.] ; Origins of stochastic intracellular processes and consequences for cell-to-cell variability and cellular survival strategies / A. Schwabe ... [et al.] -- section 9. Managing systems biology data, models and research. The SEEK : a platform for sharing data and models in systems biology / Katy Wolstencroft ... [et al.] ; Crossing the boundaries : delivering trans-disciplinary science in a disciplinary world / Elizabeth A. Elliot and Neil W. Hayes
Bibliography Includes bibliographical references and indexes
Notes Online version of the print title
Mode of access: World Wide Web
System requirements: Internet connectivity, World Wide Web browser, and Adobe Acrobat reader
Subject Systems biology.
Form Electronic book
Author Jameson, Daniel.
Verma, Malkhey.
Westerhoff, Hans V.
ISBN 0123851181 (hbk.)
9780123851185 (hbk.)