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Title Chimpanzees in biomedical and behavioral research : assessing the necessity / Committee on the Use of Chimpanzees in Biomedical and Behavioral Research, Board on Health Sciences Policy, Institute of Medicine, Board on Life Sciences, Division on Earth and Life Studies ; Bruce M. Altevogt [and others], editors ; Institute of Medicine and National Research Council of the National Academies
Published Washington, D.C. : National Academies Press, 2011

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Description 1 online resource (x, 190 pages) : color illustrations
Contents SUMMARY -- STUDY BACKGROUND AND CONTEXT -- Origin of Study and Committee Statement of Task -- Ethical Considerations -- METHODS AND ORGANIZATION OF THE REPORT -- INTERNATIONAL POLICIES GUIDING CHIMPANZEE USE -- SUMMARY OF CHIMPANZEE RESEARCH -- Analysis of Federally Supported Research -- Analysis of Private-Sector Supported Research -- Criteria That Guide the Current Use of Chimpanzees -- PRINCIPLES GUIDING THE USE OF CHIMPANZEES IN RESEARCH -- Ethologically Appropriate Physical and Social Environments -- Criteria to Assess the Necessity of the Chimpanzee for Biomedical -- Research -- Criteria for Use of the Chimpanzee in Comparative Genomics and -- Behavioral Research -- REVIEWING THE NECESSITY OF CURRENT CHIMPANZEE -- RESEARCH -- Monoclonal Antibodies -- Development of Chimpanzee Monoclonal Antibodies -- Safety Testing of Monoclonal Antibody Therapies -- Respiratory Syncytial Virus -- HCV Antiviral Drugs -- Therapeutic HCV Vaccine -- Prophylactic HCV Vaccine -- Comparative Genomics -- Altruism -- Cognition -- FUTURE USE OF CHIMPANZEES IN BIOMEDICAL AND -- BEHAVIORAL RESEARCH 64 -- CONCLUSIONS AND RECOMMENDATIONS 66 -- APPENDIXES -- A References -- B Commissioned Paper: Comparison of Immunity to Pathogens in Humans, Chimpanzees, and Macaques -- C Information-Gathering Agendas -- D Committee Biographies
Summary "For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future"--Publisher description
Bibliography Includes bibliographical references
Notes Online resource; title from resource t.p. (National Academies Press, viewed Dec. 27, 2011)
Subject Chimpanzees as laboratory animals.
Chimpanzees as laboratory animals -- Moral and ethical aspects
Chimpanzees.
Laboratory animals.
Animal Experimentation -- ethics
Pan troglodytes
Animal Testing Alternatives -- ethics
Animals, Laboratory
Ethics, Research
Models, Animal
Pan troglodytes (species)
MEDICAL -- Research.
Laboratory animals
Chimpanzees
Chimpanzees as laboratory animals
Form Electronic book
Author Altevogt, Bruce M.
Committee on the Use of Chimpanzees in Biomedical and Behavioral Research (U.S.)
LC no. 2012359354
ISBN 9780309220408
0309220408