Title Human fungal pathogens / edited by Oliver Kurzai

Edition Second edition Published Berlin : Springer, 2014

Table of Contents
	Basics of Fungal Virulence
1.	From Commensal to Pathogen: Candida albicans / Bernhard Hube					3
2.	Aspergillus fumigatus: Saprotroph to Pathogen / Elaine Bignell					19
3.	Systems Biology Approaches to Understanding and Predicting Fungal Virulence / Karl Kuchler					45
	Immune Response to Fungal Infections
4.	Receptor--Ligand Interactions in Fungal Infections / Gordon D. Brown					77
5.	Macrophages in the Immune Response Against Cryptococcus / Robin C. May					97
6.	T Cell Responses in Fungal Infections / Agostinho Carvalho					109
7.	Molecular Mechanisms of Histoplasma Pathogenesis / Chad A. Rappleye					129
8.	Visualizing Immune Responses in Fungal Infections: Established and Novel Methods / Matthias Gunzer					141
9.	Mucosal Immunology in Candida albicans Infection / Martin Schaller					161
	Clinical Presentations and Epidemiology of Fungal Infections
10.	Invasive Aspergillosis in the Intensive Care Unit / Wouter Meersseman					179
11.	Molecular Epidemiology of Pneumocystis Outbreaks / Joseph A. Kovacs					191
12.	Infections Caused by Mucorales / Malcolm D. Richardson					205
13.	Diagnostics of Fungal Infections / Oliver Kurzai					229
	Treatment of Fungal Infections
14.	Therapeutic Strategies in Fungal Infections / Oliver A. Cornely					263
15.	Antifungal Pharmacokinetics / Oliver A. Cornely					281
	Biosystematic Index					291
	Subject Index					293

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Description 1 online resource Series The mycota ; XII Mycota ; 12. Contents From Commensal to Pathogen: Candida albicans -- Aspergillus fumigatus: Saprotroph to Pathogen -- Systems Biology Approaches to Understand and Predict Fungal Virulence -- Receptor-Ligand Interactions in Fungal Infections -- Macrophages in the Immune Response against Cryptococcus -- T Cell Responses in Fungal Infections -- Molecular Mechanisms of Histoplasma Pathogenesis -- Visualizing Immune Responses in Fungal Infections Established and Novel Methods -- Mucosal Immunology in Candida albicans Infection -- Invasive Aspergillosis in the Intensive Care Unit -- Molecular Epidemiology of Pneumocystis Outbreaks -- Infections Caused by Mucorales -- Diagnostics of Fungal Infections -- Therapeutic Strategies in Fungal Infections -- Antifungal Pharmacokinetics Summary Whereas plant and insect infections are commonly caused by fungi, only a small minority of the vast diversity of fungal species is pathogenic to humans. Despite this, fungal infections cause considerable morbidity and mortality worldwide. This volume is dedicated to the biology, clinical presentation and management of invasive fungal infections. Major pathogenic fungi are introduced by world-leading experts and the basic principles of fungal virulence are reviewed in the light of new results and experimental technologies that offer unprecedented insights into invasive infections caused by Aspergillus, Candida, Cryptococcus, Pneumocystis and Mucorales. In parallel, the clinical presentation of invasive fungal infections and current approaches to their diagnosis and treatment are summarized to provide an overview of human pathogenic fungi, linking pathogen biology to the clinical presentation of disease Notes Includes indexes Print version record Subject Pathogenic fungi. Medical mycology. HEALTH & FITNESS -- Diseases -- General. MEDICAL -- Clinical Medicine. MEDICAL -- Diseases. MEDICAL -- Evidence-Based Medicine. MEDICAL -- Internal Medicine. Medical mycology Pathogenic fungi Form Electronic book Author Kurzai, Oliver, editor ISBN 9783642394324 3642394329

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