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Title Immunomic discovery of adjuvants and candidate subunit vaccines / edited by Darren R. Flower, Yvonne Perrie
Published New York : Springer, ©2013

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Description 1 online resource
Series Immunomics reviews ; 5
Immunomics reviews ; v. 5.
Contents Immunomic Discovery of Adjuvants, Delivery Systems, and Candidate Subunit Vaccines: A Brief Introduction / Darren R. Flower, Yvonne Perrie -- Bacterial Genomes and Vaccine Design / Valeria Cafardi, John L. Telford -- Identification of Candidate Vaccine Antigens In Silico / Darren R. Flower, Matthew N. Davies -- Post-genomic Antigen Discovery: Bioinformatical Approaches to Reveal Novel T Cell Antigens of Mycobacterium bovis / Martin Vordermeier, Gareth J. Jones -- Genome-Based Computational Vaccine Discovery by Reverse Vaccinology / Yongqun He -- Computational Prediction of Protein Subcellular Localization, Genomic Islands, and Virulence to Aid Antigen Discovery / Bhavjinder K. Dhillon, Nancy Y. Yu -- On the Development of Vaccine Antigen Databases: Progress, Opportunity, and Challenge / Hifzur Rahman Ansari, Darren R. Flower -- What Have Dendritic Cells Ever Done for Adjuvant Design? Cellular and Molecular Methods for the Rational Development of Vaccine Adjuvants / Alexander D. Edwards -- Towards the Systematic Discovery of Immunomodulatory Adjuvants / Darren R. Flower -- Designing Liposomes as Vaccine Adjuvants / Malou Henriksen-Lacey, Yvonne Perrie -- Designing Nonionic Surfactant Vesicles for the Delivery of Antigens for Systemic and Alternative Delivery Routes / Jitinder Wilkhu, Anil Vangala -- Immune Stimulating Complexes (ISCOMs) and Quil-A Containing Particulate Formulations as Vaccine Delivery Systems / S. Hook, T. Rades -- Formulation and Characterisation of PLGA Microspheres as Vaccine Adjuvants / Daniel J. Kirby, Randip Kaur, Yvonne Perrie -- Powder Vaccines for Pulmonary Delivery / Tom Jin, Eric Tsao
Summary Vaccine discovery is one of the most exciting and fast-moving areas of applied science. Since Edward Jenner's work in the 18th century, vaccines have transformed health across the globe. Bringing together clinical, experimental, and computational disciplines vaccinology addresses the most pressing needs of 21st century health-care: the great infectious diseases threatening the developing world, such as HIV, Malaria, and TB; and chronic diseases, such as dementia, threatening the developed world. This volume seeks to expand the horizons of vaccine design and discovery by highlighting cutting edge work in three areas of vaccinology: the rational discovery of subunit vaccines, the identification of adjuvants, and the delivery of vaccines via state-of-the-art nanotechnology
Bibliography Includes bibliographical references and index
Notes English
Print version record
In Springer eBooks
Subject Vaccines.
Immunological adjuvants.
Antigens.
Vaccines -- Design -- History
Vaccines
Adjuvants, Immunologic
Antigens
Vaccines -- pharmacology
Vaccines -- history
Vaccines, Subunit
MEDICAL -- Pharmacology.
Antigens
Immunological adjuvants
Vaccines
Vaccines -- Design
Genre/Form History
Form Electronic book
Author Flower, Darren R
Perrie, Yvonne
LC no. 2012949423
ISBN 9781461450702
1461450705
1461450691
9781461450696
1283933853
9781283933858