| Description |
1 online resource |
| Series |
2012-2013 Springer E-Books - Biomedical & Life Sciences
|
| Contents |
pt. 1. INTRODUCTION -- Lectins: An Overview -- pt. 2. INTRACELLULAR LECTINS -- Lectins in Quality Control: Calnexin and Calreticulin -- P-Type Lectins: Cation-Dependent Mannose-6-Phosphate Receptor -- P-Type Lectins: Cation-Independent Mannose-6-Phosphate Reeptors -- Mannose-6-Phosphate Receptor Homologous Protein Family -- Lectins of ERAD Pathway: F-Box Proteins and M-Type Lectins -- pt. 3. L-TYPE LECTINS -- L-Type Lectins in ER-Golgi Intermediate Compartment -- Pentraxins: The L-Type Lectins and the C-Reactive Protein as a Cardiovascular Risk -- pt. 4. ANIMAL GALECTINS -- Overview of Animal Galectins: Proto-Type Subfamily -- Galectin-1: Forms and Functions -- Tandem-Repeat Type Galectins -- Galectin-3: Forms, Functions, and Clinical Manifestations -- Galectin-3: A Cancer Marker with Therapeutic Applications -- pt. 5. R-TYPE ANIMAL LECTINS -- R-Type Lectin Families -- Mannose Receptor Family: R-Type Lectins 50580 pt. 6. I-TYPE LECTINS -- I-Type Lectins: Sialoadhesin Family -- CD33 (Siglec 3) and CD33-Related Siglecs -- pt. 7. NOVEL SUPER-FAMILIES OF LECTINS -- Fibrinogen Type Lectins -- Chi-Lectins: Forms, Functions and Clinical Applications -- Novel Groups of Fuco-Lectins and Intlectins -- Annexins (Lipocortins) -- pt. 8. C-TYPE LECTINS: Collectins -- C-Type Lectins Family -- Collectins: Mannan-Binding Protein as a Model Lectin -- Pulmonary SP-A: Forms and Functions -- Surfactant Protein-D -- pt. 9. C-Type Lectins: Selectins -- L-Selectin (CD62L) and Its Ligands -- P-Selectin and Its Ligands -- E-Selectin (CD62E) and Associated Adhesion Molecules -- pt. 10. C-Type Lectins: Lectin Receptors on NK Cells -- KLRB Receptor Family and Human Early Activation Antigen (CD69) -- NKG2 Subfamily C (KLRC) -- NKG2D Activating Receptor -- KLRC4, KLRG1, and Natural Cytotoxicity Receptors 50580 pt. 11. C-Type Lectins: Endocytic Receptors -- Asialoglycoprotein Receptor and the Macrophage Galactose-Type Lectin -- Dectin-1 Receptor Family -- Dendritic Cell Lectin Receptors (Dectin-2 Receptors Family) -- DC-SIGN Family of Receptors -- pt. 12. C-Type Lectins: Proteoglycans -- Lectican Protein Family -- Proteoglycans of the Central Nervous System -- pt. 13. C-Type Lectins: Emerging Groups of C-Type Lectins -- Regenerating (Reg) Gene Family -- Emerging Groups of C-Type Lectins -- Family of CD93 and Recently Discovered Groups of CTLDs -- pt. 14. CLINICAL SIGNIFICANCE OF ANIMAL LECTINS -- MBL Deficiency as Risk of Infection and Autoimmunity -- Pulmonary Collectins in Diagnosis and Prevention of Lung Diseases -- Selectins and Associated Adhesion Proteins in Inflammatory disorders -- Polycystins and Autosomal Polycystic Kidney Disease -- Endogenous Lectins as Drug Targets |
| Summary |
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular distribution, molecular structure, gene organization, possible functions, clinical applications, lectin-ligand interactions and their intervention for therapeutic purposes are provided. The recently discovered C-type lectins as well as further novel super-families of this group of molecules are described in detail. Furthermore, the clinical significance of animal lectins in inflammatory diseases, defects of immune defense and autoimmunity are described and their application as drugs and therapeutic targets is discussed. With the increasing interest in lectins in biomedical research and their therapeutic applications, this book on animal lectins and associated proteins is a must have for researchers in the area |
| Analysis |
Life sciences |
|
Immunology |
|
Biochemistry |
|
RNA-ligand interactions |
|
Protein-Ligand Interactions |
|
Protein Science |
| Bibliography |
Includes bibliographical references |
| Notes |
English |
| Subject |
Lectins.
|
|
Lectins
|
|
SCIENCE -- Life Sciences -- Biochemistry.
|
|
Lectins
|
| Form |
Electronic book
|
| Author |
Gupta, Anita
|
|
Gupta, Rajesh K
|
| ISBN |
9783709110652 |
|
3709110653 |
|
9783709110645 |
|
3709110645 |
|
