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Title Controversies in acute kidney injury / volume editors, John A. Kellum, Claudio Ronco, Jean-Louis Vincent
Published Basel ; New York : Karger, ©2011

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Description 1 online resource (vii, 258 pages) : illustrations (some color)
Series Contributions to nephrology, 0302-5144 ; v. 174
Contributions to nephrology ; v. 174.
Contents Cover; Contents; Unveiling Current Controversies inAcute Kidney Injury; Prerenal Azotemia Syndromes; Analysis of the Prerenal Contributionsto Acute Kidney Injury; Abstract; Determinants of Ultrafiltration; Neurohormonal Interactions and Their Contribution to Prerenal Acute Kidney Injury; Conclusion; Acknowledgements; References; The Role of Tubuloglomerular Feedback in the Pathogenesis of Acute Kidney Injury; Abstract; Overview of Tubuloglomerular Feedback; Role of Tubuloglomerular Feedback in the Pathogenesis of Acute Kidney Injury; Conclusion; Acknowledgements; References
Can We Identify Prerenal Physiology and Does It Matter?Abstract; The Classic Paradigm of Prerenal Azotemia: Definitions and Concepts; The Flaws of This Paradigm; Histological Patterns; Epidemiology Data; Mechanism of Prerenal Azotemia; Are Biomarkers Useful to Clarify Such a Paradigm?; References; Cardiorenal Syndrome: A Complex Series of Combined Heart/Kidney Disorders; Abstract; The Definition or Classification of Cardiorenal Syndromes; Pathophysiology of Cardiorenal Syndromes; Management of Cardiorenal Syndrome; Conclusions; References; Hepatorenal Syndrome; Abstract
Diagnosis of Hepatorenal SyndromePathophysiology of Hepatorenal Syndrome; Treatment of Hepatorenal Syndrome; Conclusions; References; Dying 'of' or 'with' Acute Kidney Injury; Clinical Consequences of Acute Kidney Injury; Abstract; Morbidity Caused by Acute Kidney Injury; Inflammation and 'Organ Crosstalk'; Acidosis; Electrolyte Abnormalities; Infection; Inadequate Antimicrobial Therapy; Inadequate Metabolic and Nutritional Support; Conclusion; References; Renal-Pulmonary Crosstalk; Abstract; The Effect of Acute Kidney Injury on Pulmonary Function
The Effect of Acute Lung Injury on Renal FunctionConclusions; References; Acute Kidney Injury, Acute Lung Injury and Septic Shock: How Does Mortality Compare?; Abstract; Mortality from Acute Kidney Injury; Mortality from Severe Sepsis; Mortality from Acute Respiratory Failure; Mortality from Multiple Organ Failure; Conclusion; References; Sepsis and Acute Kidney Injury Are Bidirectional; Abstract; Sepsis and Acute Kidney Injury: Clinical Problem; Mechanisms of Bidirectional Interplay between Sepsis and Acute Kidney Injury; Conclusion; Acknowledgement; References
Pathophysiology of Sepsis-Induced Acute Kidney InjuryPathophysiology of Sepsis- Induced Acute Kidney Injury: The Role of Global Renal Blood Flow and Renal Vascular Resistance; Abstract; Is Sepsis- Induced Acute Kidney Injury Due to Decreased Renal Blood Flow?; Is Sepsis- Associated Acute Kidney Injury Due to Increased Renal Vascular Resistance?; Conclusion; References; Septic Acute Kidney Injury: The Glomerular Arterioles; Abstract; The Pathogenesis of Septic Acute Kidney; The Primacy of Renal Blood Flow; Intrarenal Hemodynamic Changes
Summary Acute kidney injury (AKI) is a serious and as yet incompletely understood disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions. This disorder is very common in (elderly) ICU patients and is associated with very high mortality. Many of those who survive suffer from permanent kidney failure and other long-term morbidities, which may include cardiovascular disease and immune dysfunction. Epidemiologic evidence suggests that AKI is not a single disease, but a syndrome comprised of multiple, often coexisting, etiologies. Being usually part of multiorgan failure syndrome, it calls for multiple organ support therapy. The publication at hand contains sections on prerenal azotemia syndromes, dying 'of' or 'with' AKI, pathophysiology of sepsis-induced acute kidney injury, developments in prevention / treatment / rehabilitation, and renal support. Reporting the latest recommendations from experts, it provides valuable information for those that are interested in understanding the disorder and its treatment options
Bibliography Includes bibliographical references and indexes
Subject Acute renal failure.
Kidneys -- Wounds and injuries
Acute Kidney Injury -- physiopathology
Acute Kidney Injury
Acute Kidney Injury -- therapy
Renal Replacement Therapy
MEDICAL -- Surgery -- General.
Acute renal failure
Kidneys -- Wounds and injuries
Form Electronic book
Author Kellum, John A
Ronco, C. (Claudio), 1951-
Vincent, J. L
ISBN 9783805598118
3805598114
1280670916
9781280670916
9783805598101
3805598106