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Title Proteomics in nephrology : towards clinical applications / volume editor, Visith Thongboonkerd
Published Basel ; New York : Karger, 2008

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Description 1 online resource
Series Contributions to nephrology, 0302-5144 ; v. 160
Contributions to nephrology ; v. 160. 0302-5144
Contents Proteomics for the investigation of acute kidney injury / P. Devarajan -- Proteomics of plasma and urine in primary nephrotic syndrome in children / G. Candiano [and others] -- Urinary proteome profiling to search for biomarkers in steroid-resistant nephrotic syndrome / A.Z. Traum, A.D. Schachter -- Searching for novel biomarkers and new therapeutic targets of diabetic nephropathy using proteomics approaches / V. Thongboonkerd -- Diagnostic and prognostic biomarkers in acute renal failure / J.M. Arthur [and others] -- Proteomics and renal transplantation : searching for novel biomarkers and therapeutic targets / S. Schaub, J.A. Wilkins, P. Nickerson -- Metabolomics : a complementary tool in renal transplantation / D.S. Wishart
Understanding and managing renal cell carcinoma : can proteomic studies contribute to clinical practice? -- R.A. Craven, R.E. Banks -- Capillary electrophoresis coupled to mass spectrometry for biomarker discovery and diagnosis of kidney diseases / P. Zürbig, H. Mischak -- Identification of urinary biomarkers by proteomics in newborns : use in obstructive nephropathy / S. Decramer [and others] -- Proteomics and kidney stone disease / V. Thongboonkerd -- Exploring the uremic toxins using proteomic technologies / E. Schiffer -- Proteomic approaches for the study of cell signaling in the renal collecting duct / E.J. Hoorn -- Overview of kidney and urine proteome databases / Y. Yoshida [and others]
Summary Since the publication of the first volume on proteomics in nephrology, methodologies and protocols for renal and urinary proteome analyses have been continuously improved, resulting in considerable progress towards clinical application. Proteomics not only contributes to a better understanding of the renal physiology and pathogenic mechanisms of kidney diseases, but also assists in the search for novel biomarkers for diagnostics and prognostics and supports the definition and development of new therapeutic targets and drugs for better therapeutic outcome. While the first volume focused mainly on an overview, technologies and methodologies, this volume highlights successful applications of proteomics to several kidney diseases, including acute kidney injury, nephrotic syndrome, diabetic nephropathy, renal allograft rejection, renal cell carcinoma, obstructive nephropathy, kidney stone disease, uremia, and others. Written by acclaimed experts in proteomics and nephrology, this book is an excellent resource of references for nephrologists, clinicians, pharmacists, other healthcare professionals, proteomists, physiologists, scientists, and trainees
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Kidneys -- Diseases.
Proteomics.
Biochemical markers.
Kidney Diseases -- physiopathology
Proteome -- analysis
Proteomics -- methods
Kidney Diseases
Proteomics
Biomarkers
Biochemical markers
Kidneys -- Diseases
Proteomics
Form Electronic book
Author Thongboonkerd, Visith.
S. Karger (Firm)
ISBN 9783805585453
3805585454