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Author Monchaud, David

Title Biological Relevance & Therapeutic Applications of DNA- & RNA-Quadruplexes / David Monchaud
Published Université de Bourgogne, France : Future Science Ltd, 2015, ©2015

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Description 1 online resource (242 pages)
Contents Biological relevance and therapeutic applications of DNA- and RNA-quadruplexes : double helix versus quadruple helix / David Monchaud -- Existence of G-quadruplexes in cells / Sébastien Britton, Alexandra Bartoli & Raphaël Rodriguez -- Diversity of DNA and RNA G-quadruplex structures / Primož Šket and Janez Plavec -- Direct observation of G-quadruplexes using DNA origami nanoscaffold / Arivazhagan Rajendran, Yue Li, Masayuki Endo & Hiroshi Sugiyama -- The G-factor : role of G-quadruplexes in genomic instability and cancer / Mrinal Srivastava & Sathees C. Raghavan -- Assessing the biological relevance of G-quadruplexes in telomeres by specific quadruplex-binding proteins / Takanori Oyoshi -- G-quadruplex dynamics : assays for intramolecular G-quadruplex helicases and inhibitors / Sean M Kerwin & Wendi M. David -- Proteins that interact with DNA and RNA G-quadruplexes / Aaron L. Moye & Tracy M. Bryan -- Biological relevance and small molecule targeting of RNA G-quadruplexes in the human genome / Anthony Bugaut -- Biological mechanisms of action of G-quadruplex targeting agents / Kyle R. Hukezalie, Elwy Okaz & Judy M.Y. Wong -- How has the field of quadruplex ligands fared since 1997? / Xiaogang Qu, Ta-Chau Chang, Kogularamanan Suntharalingam & David Monchaud -- Chiral compounds targeting G-quadruplexes / Chuanqi Zhao & Xiaogang Qu -- Novel metal-containing molecules that target DNA G-quadruplexes / Kogularamanan Suntharalingam -- Novel molecules targeting DNA G-quadruplexes : carbazole derivatives / Ta-Chau Chang, Zi-Fu Wang, Ting-Yuan Tseng & Cheng-Chung Chang -- Nature-inspired strategies to target DNA/RNA-quadruplexes / Aurelien Laguerre, Loic Stefan & David Monchaud -- DNA G-quadruplexes under the spotlight / Mazen Haj Sleiman & Sylvain Ladame -- G-quadruplex DNA for the construction of sensing platforms / Dik-Lung Ma, Modi Wang, Li-Juan Liu, Sheng Lin, Lihua Lu, Daniel Shiu-Hin Chan & Chung-Hang Leung
Bibliography Includes bibliographical references
Subject RNA -- Research
DNA -- Analysis
G-Quadruplexes
DNA -- Analysis.
RNA -- Research.
Form Electronic book
ISBN 9781910419687
1910419680
9781910419694
1910419699