Description |
1 online resource (xx, 425 pages, 4 unnumbered pages of plates) : illustrations (some color) |
Contents |
Frontmatter -- Color Plates -- Introduction to Assay Development -- Measurement and Instrumentation -- Fundamental Principles of Assay Development with Isolated Proteins -- Separation-Based Techniques in Bioassays -- General Protein Binding Assay Formats -- Functional Assays with Isolated Proteases -- Functional Assays for Protein Kinases -- Fundamental Principles of Cell-Based Assays -- Functional Ion Channel Assays -- Assays with GPCRs -- Assays Based on Integrated Cell System Properties -- High-Content Cell-Based Assay with Optical Imaging Techniques -- High-Throughput Screening -- Case Study: Development of a Microfluidic-Based Kinase Assay Platform -- Index |
Summary |
Essential principles and practice of assay development. The first comprehensive, integrated treatment of the subject, Assay Development: Fundamentals and Practices covers the essentials and techniques involved in carrying out an assay project in either a biotechnology/drug discovery setting or a platform setting. Rather than attempting comprehensive coverage of all assay development technologies, the book introduces the most widely used assay development technologies and illustrates the art of assay development through a few commonly encountered biological targets in assay development (e.g., p |
Bibliography |
Includes bibliographical references and index |
Notes |
English |
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Print version record |
Subject |
Biological assay.
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Aquatic biology.
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Biological Assay
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MEDICAL -- Biochemistry.
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Aquatic biology
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Biological assay
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Form |
Electronic book
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LC no. |
2009031386 |
ISBN |
9780470583128 |
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0470583126 |
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9780470191156 |
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0470191155 |
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9780470583111 |
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0470583118 |
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1282656511 |
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9781282656512 |
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9786612656514 |
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6612656514 |
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