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Title Rational pharmacotherapy of the inner ear / volume editors, D. Felix, E. Oestreicher
Published Basel ; New York : Karger, 2002

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Description 1 online resource (x, 168 pages) : illustrations (some color)
Series Advances in oto-rhino-laryngology, 0065-3071 ; v. 59
Advances in oto-rhino-laryngology ; v. 59. 0065-3071
Contents Machine generated contents note: 1 Anatomical Differences in the Peripheral Auditory System of Mammals and Man -- Felix, H. (Zfirich) -- 11 Neurotransmission in the Human Labyrinth -- Schrott-Fischer, A.; Kammen-Jolly, K.; Scholtz, A.W. (Innsbruck); -- Kong, W.-J. (Hua-Zhong); Eybalin, M. (Montpellier) -- 18 Different Action of Memantine and Caroverine on Glutamatergic Transmission in the Mammalian Cochlea -- Oestreicher, E. (Munich/Berne); Ehrenberger, K. (Vienna); Felix, D. (Berne) -- 26 Role of Substance P in the PeripheralVestibular and Auditory System -- Felix, H. (Zirich); Oestreicher, E. (Munich/Berne); Felix, D. (Berne); -- Ehrenberger, K. (Vienna) -- Hair Cells -- Ion Channels -- 35 Calcium Channels in Mouse Hair Cells: Function, Properties and Pharmacology -- Engel, J.; Michna, M. (Tiibingen); Platzer, J.; Striessnig, J. (Innsbruck) -- 42 Adrenergic and Muscarinic Control of Cochlear Endolymph Production -- Wangemann, P. (Manhattan) -- 51 Cochlear Blood Flow Regulation -- Wangemann, P. (Manhattan) -- 58 ETA Receptors in the Gerbil Spiral Modiolar Artery -- Scherer, E.Q.; Wangemann, P. (Manhattan) -- Immunology -- Cell Cycle -- 66 Immunological Damage to the Inner Ear: Current and Future Therapeutic Strategies -- Ryan, A.F. (San Diego/La Jolla); Pak, K.; Low, W; Battaglia, A.; Mullen, L.; -- Harris, J.P.; Keithley, E.M. (San Diego) -- 75 Pharmacological Influence on Inner Ear Endothelial Cells in Relation to the Pathogenesis of Sensorineural Hearing Loss -- Gloddek, B.; Lamm, K.; Arnold, W. (Munich) -- 84 Mpv17 Mouse Strain -A Model for the Relationship between the Kidney and the Inner Ear -- Meyer zum Gottesberge, A.M.; Balz, V. (Diisseldorf); Felix, H. (Zurich) -- Ototoxicity, Noise and Aging -- 91 Sensitivity to Glutamate Neurotoxicity in Different Developmental Periods of the Rat Cochlea -- Carricondo, F; Bartolome, M.V; Vicente-Torres, M.A.; Fernmndez-Pacheco, P.; -- Rodriguez, T.; Gil-Loyzaga, P. (Madrid) -- 96 Protective Mechanisms of Sound Conditioning -- Niu, X.; Canlon, B. (Stockholm) -- 106 Effects of Aging on C57BL/6J Mice: An Electrophysiological and Morphological Study -- Bartolom6, M.V; del Castillo, E.; L6pez, L.M.; Carricondo, F.; Poch-Broto, J.; -- Gil-Loyzaga, P. (Madrid) -- 112 Effects of Aging on Cochlear MonoamineTurnover -- Vicente-Torres, M.A.; Davila, D.; Mufioz, E.; Gil-Loyzaga, P. (Madrid) -- 116 Degeneration Pattern of Human First-Order Cochlear Neurons -- Felix, H.; Pollak, A. (Zfirich); Gleeson, M. (London); Johnsson, L.-G. (Helsinki) -- 124 The Inner Hair Cell Afferent/Efferent Synapses Revisited: A Basis for New Therapeutic Strategies -- Puel, J.-L.; Ruel, J.; Guitton, M.; Pujol, R. (Montpellier) -- 131 Neurotransmission of the Cochlear Inner Hair Cell Synapse -- Implications for Inner Ear Therapy -- Oestreicher, E. (Munich/Berne); Arnold, W. (Munich); Felix, D. (Berne) -- 140 Simulation of Methods for Drug Delivery to the Cochlear Fluids -- Salt, A.N. (St. Louis) -- 149 Transtympanic Endoscopy for Drug Delivery to the Inner Ear Using a New Microendoscope -- Plontke, S.K.-R. (Tuibingen); Plinkert, PK.; Plinkert, B. (Tiibingen/Homburg, Saar); -- Koitschev, A.; Zenner, H.-P.; L6wenheim, H. (Tiibingen) -- 156 Clinical Experience with Caroverine in Inner Ear Diseases -- Ehrenberger, K. (Vienna)
Summary Rational pharmacotherapy of the inner ear will become an important issue in treatment of inner ear diseases today and in the future. The contributions of some of the experts in the field are gathered in the present volume dedicated to all aspects of the pharmacology and the possible local and systemic treatment of inner ear diseases. Major topics include new aspects of human inner ear anatomy, neurotransmission, ion channels, vascular system, immunology, excitotoxicity, modulation of cell cycle, regeneration and differentiation, as well as new aspects of basic mechanisms at the cellular and molecular levels. A major feature of this volume is that it brings together both basic researchers and physicians to evaluate new experimental therapies and discuss future clinical strategies in the treatment of cochleo-vestibular disorders. Therefore, it will prove interesting to both scientists and clinicians in sensory physiology and auditory systems
Bibliography Includes bibliographical references and indexes
Subject Labyrinth (Ear) -- Diseases -- Chemotherapy
Ear, Inner -- physiology
Labyrinth Diseases -- drug therapy
Form Electronic book
Author Felix, D. (Dominik)
Oestreicher, E. (Elmar)
S. Karger (Firm)
ISBN 9783318007527
3318007528