| Description |
1 online resource (xiii, 195 pages) : illustrations (some color) |
| Series |
Advances in experimental medicine and biology, 2214-8019 ; volume 1218 |
|
Advances in experimental medicine and biology ; v. 1218. 0065-2598
|
| Contents |
Notch signaling and tissue patterning in embryology: an introduction -- Notch signaling and embryonic development: an ancient friend, revisited -- The five faces of Notch signalling during Drosophila melanogaster embryonic CNS development -- Epigenetic regulation of Notch signaling during Drosophila development -- Regulation of proneural wave propagation through a combination of Notch-mediated lateral inhibition and EGF-mediated reaction diffusion -- A nucleolar protein, Nepro, is essential for the maintenance of early neural stem cells and preimplantation embryos -- Role of Notch signaling in leg development in Drosophila melanogaster -- Notch signalling: the multitask manager of inner ear development and regeneration -- Notch pathway and inherited diseases: challenge and promise |
| Summary |
"This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch's role in the development of the embryo to the Notch signaling pathway's role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch's role in senescence, the regulation of Notch signaling by microRNAs, Notch's role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books - Molecular Biology of Notch Signaling and Notch Signaling in Cancer - this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students"--Publisher's description |
| Notes |
Updated and expanded edition of Notch signaling in embryology and cancer published by Landes and Springer in 2012 in Advances in experimental medicine and biology, volume 727. Volume 1 is Molecular biology of Notch signaling, Volume II is Notch signaling in embryology, and Volume III is Notch signaling in cancer |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from electronic title page (ProQuest Ebook Central, viewed on June 22, 2021) |
| Subject |
Cellular signal transduction.
|
|
Receptors, Notch -- metabolism
|
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Growth and Development
|
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Signal Transduction -- physiology
|
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Signal Transduction
|
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Cellular signal transduction
|
| Form |
Electronic book
|
| Author |
Reichrath, J. (Jörg), 1962- editor.
|
|
Reichrath, Sandra, 1974- editor.
|
| ISBN |
9783030344368 |
|
3030344363 |
|
9783030344375 |
|
3030344371 |
|
