STAR trek : an introduction to STAR family proteins and review of QKI / Karen Artzt and Jiang I. Wu -- The STAR family member : quaking (QKI) and cell signaling / Yue Feng and Andrew Bankston -- Insights into the structural basis of RNA : recognition by STAR domain proteins / Sean P. Ryder and Francesca Massi -- Post-translational regulation of STAR proteins and effects on their biological functions / Claudio Sette -- Expression and fuctions of the STAR proteins Sam68 and T-star in mammalian spermatogenesis / Ingrid Ehrmann and David J. Elliott -- The role of quaking in mammalian embryonic development / Monica J. Justice and Karen K. Hirschi -- Drosophila STAR proteins : what can be learned from flies? / Talila Volk -- C. elegans STAR proteins, GLD-1 and ASD-2, regulate specific RNA targets to control development / Min-Ho Lee and Tim Schedl -- The branchpoint binding protein : in and out of the spliceosome cycle / Brian C. Rymond -- Reaching for the STARs : linking RNA binding proteins to diseases / Stephane Richard
Summary
This book aims to bring to the forefront a field that has been developing since the late 1990s called the STAR pathway for Signal Transduction and Activation of RNA. It is a signaling pathway that targets RNA directly; in contrast to the canonical signal - kinase cascade - transcription factor - DNA - RNA. It is proposed to allow quick responses to environment changes such as those necessary in many biological phenomenon such as the nervous system and during development