| Description |
1 online resource (xlvii, 714 pages) : illustrations, portraits |
| Series |
Advances in experimental medicine and biology, 0065-2598 ; 664 |
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Advances in experimental medicine and biology ; v. 664.
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| Contents |
pt. 1. Basic science underlying retinal degeneration.-- Analysis of genes differentially expressed during retinal degeneration in three mouse models / Ygita Kanan, Michael Centola, Frank Bart, Muayyad R. Al-Ubaidi.-- Regulation of angiogenesis by macrophages / Rajendra S. Apte.-- Protein kinase C regulates rod photoreceptor differentiation through modulation of STAT3 signaling / Carolina Pinzon-Guzman, Samuel Shaomin Zhang, Colin J. Barnstable.--Pigment epithelium-derived factor receptor (PEDF-R): a plasma membrane-linked phopholipase with PEDF binding affinity / Preeti Subramanian, Patricia M. Notario, S. Patricia Becerra.-- Function of oligomerization-incompetent RDS in rods / Dibyendu Chakraborty, Shannon M. Conley, Steven J. Fliesler, Muna I. Naash.-- Association between telomere length and sensitivity to apoptosis of HUVEC / Ji Zhang, Chen Hui, Liu Su, Wu Xiaoyen, Huang Xi, Fan Yingchuan.-- Photoreceptor guanylate cyclases and cGMP phosphodiesterases in Zebrafish / Ross F. Collery, Breandan N. Kennedy.-- RDS in cones does not interact with the beta subunit of the cyclic nucleotide gated channel / Shannon M. Conley, Xi-Qin Ding, Muina I. Naash.-- Increased expression of TGF-B1 and Smad 4 on oxygen-induced retinopathy in neonatal mice / Fan Yinchuan, Lei Chuntao, Chen Hui, Hu Jianbin.-- ZBED4. a novel retinal protein expressed in cones and Muller cells / Debora B. Farber, V.P. Theendakara, N.B. Akhmedov, M. Saghizadeh.-- Tubby-like protein 1 (Tnlp1) is required for normal photoreceptor synaptic development / Gregy H. Grossman, Gayle J.T. Pauer, Umadevi Narendra, Stephanie A. Hagstrom.-- Growth-associated protein43 (GAP43) is a biochemical marker for the whole period of fish optic nerve regeneration / Manabu Kaneda, Mikiko Nagashima, Kazuhiro Mawatari, Tomoya Nunome, Kenichiro Muramoto, Kayo Sugitani, Saroru Kato |
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Cont.-- Multiprotein complexes of retinitis pigmentosa GTPase regulator (RPGR), a ciliary protein mutated in x-linked retinitis pigmentosa (XLRP) / Carlos Murga-Zamalloa, Anand Swaroop, Hemant Khanna.-- Misfolded proteins and retinal dystrophies / Jonathan H. Lin, Matthew M. LaVail.--Neural retina and MerTK-Independent apical polarity of avB5 integrin receptors in the retinal pigment epithelium / Mallika Mallavarapu, Silvia C. Finnemann.-- Mertk in daily retinal phagocytosis: a history in the making / Emeline F. Nandrot, Eric M. Dufour.-- Interphotoreceptor retinoid binding (IRBP is essential for naormal retinoid processing in cone photoreceptors / Ryan O. Parker, Rosalie K. Crouch.-- Aseptic injury to epithelial cells alters cell surface complement regulation in the tissue specific fashion / Joshua M. Thurman, Brandon Renner, Kannan Kunchithapautham, V. Michael Holers, Barbel Rohrer.-- Role of metalloproteases in retinal degeneration induced by violet and blue light / C. Sanchez-Ramos, J.A. Vega, M.E. del Valle, A. Fernandez-Balbuena, C. Bonnin-Arias, J.M. Benitez-del Castillo.-- Mitochondrial decay and impairment of antioxidant defenses in aging RPE cells / Yuan He, Joyce Tombran-Tink.-- Ciliary transport of opsin / Deepti Trivedi, David S. Williams.-- Effect of hesperidin on expression of inducible nitric oxide synthase in cultured rabbit retinal pigment epithelial cells / Luo Xiaoting, Zeng Xiangyun, Li Shumei, Dong Minghua, Xiong Liang.-- Profiling microRNAs differentially expressed in rabbit retina / Naihong Yan, Ke M., Jia Ma, Wei Chen, Yun Wang, Guiqun Cao, Dominic Man-Kit Lam, Xuyang Liu.-- Unexpected transcriptional activity of the human VMD2 promoter in retinal development / Meili Zhu, Riccardo Natoli, Krisztina Valter, Jonathan Stone.-- Photoreceptor sensory cilia and inherited retinal degeneration / Qin Liu, Qi Zhang, Eric A. Pierce.-- Role of Elov14 protein in the biosynthesis of docosahexaenoic acid / Martin-Paul Agbaga, Richard S. Brush, MdNawajes A. Mandal, Michael H. Elliott, Muayyad R. Al-Ubaidi, Robert E. Anderson |
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Cont.-- Part. II. Molecular genetics and candidate genes.-- Molecular pathogenesis of achromatopsia associated with mutations in the cone cyclic nucleotide-gated channel CNGA3 subunit / Xi-Qin Ding, J. Browning Fitzgerald, Alexander B. Quiambao, Cynthia S. Harry, Anna P. Malykhina.-- Mutation spectra in autosomal dominant and recessive retinitis pigmentosa in northern Sweden / Irina Golovleva, Linda Kohn, Marie Burstedt, Stephen Daiger, Ola Sandgren.-- 1 Rhodopsin mutations in congenital night blindness / Suzanne D. McAlear, Timothy W. Kraft, alecia K. Gross.-- GCAP1 mutations associated with autosomal dominant cone dystrophy / Li Jiang, Wolfgang Baehr.-- Genotypic analysis of x-lined retinoschisis in western Astralia / Tina Lamey, Sarina Laurin, Enid Chelva, John De Roach.-- Mutation frequency of IMPDH1 gene of Han population in Ganzhou City / Li Shumei, Luo Xiaoting, Zeng Xiangyun, Hu Ligun, Xiong Liang, Li Sisi.-- Part. III. Diagnostic, clinical, cytopathological and physiologic aspects of retinal degeneration.-- Reversible and size-selective opening of the inner blood-retina barrier: a novel therapeutic strategy / Matthew Campbell, Anh Thi Hong, Anna-Sophia Kiang, Lawrence Tam, Paul F. Kenna, Sorcha Ni Dhubhghaill, Marian Humphries, G. Jane Farrar, Peter Humphries.-- Spectral domain optical coherence tomography and adaptive optics: imaging photoreceptor layer morphology to interpret preclinical phenotypes / Jungtae Rha, Adam M. Dubis, Melissa Wagner-Schuman, Diane M. Tait, Pooja Godara, Brett Schroeder, Kimberly Stepien, Joseph Carroll.-- Pharmacological manipulation of rhodopsin retinitis pigmentosa / Hugo F. Mendes, Raffaella Zaccarini, Michael E. Cheetham.-- Targeted high-throughput DNA sequencing for gene discovery in retinitis pigmentosa / Stephen P. Daiger, Lori S. Sullivan, Sara J. Bowne, David G. Birch, John R. Heckenlively, Eric A. Pierce, George M. Weinstock.-- Advances in imaging of Stargardt disease / Y. Chen, A. Roorda, J.L. Duncan |
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Cont.-- Protamine sulfate downregulates vascular endothelial growth factor (VEGF) and its receptor binding in vitro / Jianbin Hu, Chao Qu, Yufeng Yu, Ma Ping, Dong Wei, Dong Dandan.--Computer-assissed semi-quantitative analysis of mouse choroidal density / Yun-Zheng Le.-- Thioredoxins 1 and 2 protect retinal ganglion cells from pharmacologically induced oxidative stress, optic nerve transection and ocular hypertension / Yasunari Munemasa, Jacky M.K. Kwong, Seok H. Kim, Jae H. Ahn, Joseph Caprioli, Natik Piri.-- Near-infrared light protect the photoreceptor from light-induced damage in rats / Chao Qu, Wei Cao, Yingchuan Fan, Ying Lin.-- BDNF improves the efficacy ERG amplitude maintenance by transplantation of retinal stem cells in RCS rats / Chunyu Tian, Chuan Chuang Weng, Zheng Qin Yin.-- Role of purinergic receptors in retinal function and disease / Michelle M. Ward, Theresa Puthussery, Kirstan A. Wessey, Erica L. Fletcher.-- Part. IV. Macular degeneration.-- Fundus autofluorescence imaging in age-related macular degeneration and geographic atrophy / Srilaxmi Bearelly, Scott W. Cousins.-- Endoplasmic reticulum stress as a primary pathogenic mechanism leading to age-related macular degeneration / Jiayin Gu, Gayle J.T. Pauer, Xiuzhen Yue, Umadevi Narendra, Gwen M. Sturgill, James Bena, Xiaorong Gu, Neal S. Peachey, Robert G. Salomon, Stephanie A. Hagstrom, John W. Crabb, The Clinical Genomic, Proteomic AMD Study Group.--Impaired intracellular signaling may allow up-regulation of CTGF-synthesis and secondary peri-retinal fibrosis in human retinal pigment epithelial cells from patients with age-related macular degeneration / Piyuah C. Kothary, Jaya Badhwar, Christina Weng, Monte A. Del Monte.-- PPAR nuclear receptors and altered RPE lipid metabolism in age-related macular degeneration / Godilis Malek, Peng Hu, Albert Wielgus, Mary Dwyer, Scott Cousins.-- Pathophysiology of cigarette smoking and age-related macular degeneration / S.S. Ni Dhubhghaill, M.T. Cahill, M. Campbell, L. Cassidy, M.M. Humphries, P. Humphries.-- Oxidative stress and the ubiquitin proteolytic system in age-related macular degeneration / Scott M. Plafker.-- Slit-robo signaling in ocular angiogenesis / Haoyu Chen, Mingzhi Zhang, Shibo Tang, Nyall R. London, Dean Y. Li, Kang Zhang |
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Cont.-- Part. V. Animal models of retinal degeneration.-- Evaluation of retinal degeneration in P27KIP1 null mouse / Yumi Tokita-Ishikawa, Ryosuke Wakusawa, Toshiaki Abe.-- Differences in photoreceptor sensitivity to oxygen stress between Long Evans and Sprague-Dawley rats / Vicki Chrysostomou, Jonathan Stone, Krisztina Valter.-- Retinal degeneration in rat model of Smith-Lemli-Opitz syndrome: thinking beyond cholesterol deficiency / Steven J. Fliesler.-- Do calcium channel blockers rescue dying photoreceptors in the Pde6brd1 mouse? / Peter Barabas, Carolee Cutler Peck, David Krizaj.-- Effect of PBNA on the NO content and NOS activity in ischemia/reperfusion injury in the rat retina / Liangdong Li, Zhihua Huang, Hai Xiao, Xigui Chen, Jing Zeng.-- Recent insights into the mechanisms underlying light-dependent retinal degeneration from X. Laevis models of retinitis pigmentosa / Orson L. Moritz, Beatrice M. Tam.-- Hypoplastic retinal lamination in the purpurin knock down embryo in Zebrafish / Mikiko Nagashima, Junichi Saito, Kazuhiro Mawatari, Yusuke Mori, Toru Matsukawa, Yoshiki Koriyama, Satoru Kato.-- Functional changes in inner retinal neurons in animal models of photoreceptor degeneration / Theresa Puthussery, W. Rowland Taylor.-- Photoreceptor cell degenertation in Abcr_/_ mice / Li Wu, Taka Nagasaki, Janet R. Sparrow.-- Investigating the mechanism of disease in the RP10 form of retinitis pigmentosa / Chaterine J. Spellicy, Dong Xu, Garrett Cobb, Lizbeth Hedstrom, Sara J. Bowne, Lori S. Sullivan, Stephen P. Daiger.-- Congenital stationary night blindness in Mice -- a tale of two Cacnalf mutants / N. Lodha, S. Bonfield, N.C. Orton, C.J. Doering, J.E. McRory, S.C. Mema, R. Rehak, Y. Sauve, R. Tobias, W.K. Stell, N.T. Bech-Hansen |
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Cont.-- Protection of photoreceptors in a mouse model of RP10 / Lawrence C.S. Tam, Anna-Sophia Kiang, Naomi Chadderton, Paul F. Kenna, Matthew Campbell, Marian M. Humphries, G. Jane Farrar, Pete Humphries.-- Correlation between tissue docosahexaenoic acid levels and susceptibility to light-induced retinal degeneration / Masaki Tanito, Richard S. Brush, Michael H. Elliott, Lea D. Wicker, Kimberly R. Henry, Robert E. Anderson.-- Activation of Muller cells occurs during retinal degeneration in RCS rats / Tong Tao Zhao, Chun Yu Tian, Zheng Qin Yin.-- Effect of 3'-daidzein sulfonic sodium on the anti-oxidation of retinal ischemia/reperfusion injury in rats / Huang Zhihua, Li Liangdong, Li Xiao, Chen Fang, Zeng Jing.-- Structural and functional phenotyping in the cone-specific photoreceptor function loss 1 (cpfl1) mouse mutant -- a model of cone dystrophies / M. Dominik Fischer, Naoyuki Tanimoto, Susanne C. Beck, Gesine Huber, Karin Schaeferhoff, Stylianos Michalakis, Olaf Riess, Bernd Wissinger, Martin Biel, Michael Bonin, Mathias W. Seeliger.-- Differential role of Jak/Stat signaling in retinal degeneration / C. Lange, M. Thiersch, M. Samardzija, C. Grimm.-- Part. VI. Neuroprotection and gene therapy.-- Gene therapy in the retinal degeneration slow model of retinitis pigmentosa / Xue Cai, Shannon M. Conley, Muna I. Naash.-- PEDF promotes retinal neurosphere formation and expansion in vitro / Anna De Marzo, Claudia Aruta, Valeria Marigo.-- Multi-stage color model revisited: implications for gene therapy cure for red-green colorblindness / Katherin Mancuso, Matthew C. Mauck, James A. Kuchenbecker, Maureen Neitz, Jay Neitz.-- Achromatopsia as a potential candidate for gene therapy / Ji-Jing Pang, John Alexander, Bo Lei, Wentao Deng, Keqing Zhang, Qiuhong Li, Bo Chang, William W. Hauswirth.-- Function and mechanism of CNTF/LIF signaling in retinogenesis / Kun Do Rhee, Xian-Jie Yang.-- gp130 activation in muller cells is not essential for photoreceptor protection from light damage / Yumi Ueki, Srinivas Chollangi, Yun-Zheng Le, John D. Ash.-- Neuroprotectin D1 modulates the induction of pro-inflammatory signaling and promotes retinal pigment epithelial cell survival during oxidative stress / Jorgelina M. Calandria, Nicolas G. Bazan.-- Adeno-associated virus serotype-9 mediated retinal outer plexiform layer transduction is mainly through the photoreceptors / Bo Lei, Keqing Zhang, Yongping Yue, Arkasubhra Ghosh, Dongsheng Duan |
| Summary |
"This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy."--Books.google |
| Analysis |
geneeskunde |
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medicine |
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volksgezondheid |
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public health |
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oogheelkunde |
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ophthalmology |
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Medicine (General) |
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Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer eBooks |
| Subject |
Retinal degeneration -- Congresses
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Retinal degeneration.
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Retinal Degeneration
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MEDICAL -- Ophthalmology.
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HEALTH & FITNESS -- Vision.
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Biomédecine.
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Sciences de la vie.
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Retinal degeneration
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Netzhautdegeneration
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Chengdu
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| Genre/Form |
proceedings (reports)
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Conference papers and proceedings
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Conference papers and proceedings.
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Actes de congrès.
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| Form |
Electronic book
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| Author |
Anderson, Robert E. (Robert Eugene)
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LaVail, Matthew M.
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Hollyfield, Joe G.
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Mandal, Md. Nawajes A
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| LC no. |
2009943262 |
| ISBN |
9781441913999 |
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1441913998 |
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