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E-book

Title Factors influencing mammalian kidney development : implications for health in adult life / K.M. Moritz [and others]
Published Berlin : Springer, ©2008

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Description 1 online resource (vii, 78 pages) : illustrations
Series Advances in anatomy, embryology and cell biology, 0301-5556 ; 196
Advances in anatomy, embryology, and cell biology ; v. 196. 0301-5556
Contents Introduction -- Morphological development of the mammalian kidney -- Genetic regulation of metanephric development -- Abnormalities of renal development in the human -- Methodology to examine kidney development -- Development of function in the fetus -- Nephron endowment -- Developmental programming of the kidney -- Future directions
Summary In this monograph the authors have emphasized a number of important concepts in mammalian kidney development. Emphasis has been put on methodology so that the reader can understand how certain results or conclusions were reached and what the optimal methods for reliable results to be obtained are. In addition, as well as descriptions of the morphology there is information on the genetic basis of the structural development. In addition much attention has been paid to how nephron number may be altered by changes in the environment of the developing kidney and to the consequences for the remaining nephron gene expression and kidney function when total nephron number is altered. The consequences for the health of the adult, upon the formation of an adult kidney with altered nephron number and (potentially) gene expression, can be quite serious. The epigenetic mechanisms by which such changes can occur are introduced as a very fertile field for future investigation
Bibliography Includes bibliographical references (pages 58-78) and index
Notes English
Print version record
Subject Kidneys -- Growth
Nephrology.
Kidney -- growth & development
Kidney -- metabolism
Nephrology
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Nephrology.
Kidneys -- Growth.
Natural history.
Science.
Kidney -- growth & development.
Kidney -- metabolism.
Kidneys -- Growth
Nephrology
Form Electronic book
Author Moritz, K. M. (Karen M.)
LC no. 2008923172
ISBN 9783540777687
3540777687
1281513180
9781281513182
9786611513184
6611513183