Introduction; The Anatomical Basis of Human Cortical Development; Neuronal Miqration; Compartments of the Cortical Wall; The Cortical Hem: Signaling Center and Birthplace of CR Cells; The Reelin-Dab1 Signaling Pathway; The Cdk5/p35 Pathway; LIS1 and DCX: Key Genes for Neuronal Migration and Cortical Folding; ARX Deficiency: A Novel Type of Lissencephaly; Final Considerations: The Unique Features of Human Brain Development
Summary
The early steps in corticogenesis are decisive for the correct unfolding of neurogenesis and differentiation under tight genetic control. Here, the author outlines the events in human preplate formation, the gradual transformation of the preplate into the cortical plate and establishment of the transient compartments of the foetal cortical wall
Analysis
biomedische wetenschappen
biomedicine
humane genetica
human genetics
Medicine (General)
Geneeskunde (algemeen)
Bibliography
Includes bibliographical references (pages 84-111) and index
