Book Cover
E-book
Author Wahed, Amer, author.

Title Hematology and coagulation : a comprehensive review for board preparation, certification and clinical practice / Amer Wahed, Amitava Dasgupta
Published Amsterdam : Elsevier Inc., [2015]
©2015

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Description 1 online resource
Contents 880-01 7.2.2. Urine Electrophoresis -- 7.2.3. Immunofixation Studies -- 7.2.4. Capillary Zone Electrophoresis -- 7.2.5. Free Light-chain Assay -- 7.2.6. Paraprotein Interference in Clinical Laboratory Tests -- 7.3. Plasma Cell Neoplasm -- 7.3.1. Morphology of Plasma Cells in Myeloma -- 7.3.2. Immunophenotype of Neoplastic Plasma Cells -- 7.4. Cytogenetics in Myeloma Diagnosis -- Key Points -- References -- 8.1. Introduction -- 8.2. Flow Cytometry and Mature B Cell Lymphoid Neoplasms -- 8.2.1. B Cell Markers -- 8.3. Flow Cytometry and Mature T and Natural Killer Cell Lymphoid Neoplasms -- 8.3.1. Detection of Clonal or Restricted Populations of T and NK Celts -- 8.4. Plasma Cell Dyscrasias -- 8.5. Flow Cytometry and Acute Leukemia -- 8.5.1. Flow Cytometry and Subtypes of Acute Myeloid Leukemia -- 8.6. Flow Cytometry and Myelodysplastic Syndrome -- 8.7. Flow Cytometry and Hematogones -- Key Points -- References -- 9.1. Introduction -- 9.2. Cytogenetic Abnormalities in Chronic Myeloid Leukemia -- 9.3. Cytogenetic Abnormalities in Myelodysplastic Syndrome -- 9.4. Cytogenetic Abnormalities in Patients with Acute Myeloid Leukemia -- 9.5. Cytogenetic Abnormalities in Actute Lymphoblastic Leukemia -- 9.6. Cytogenetic Abnormalities in Multiple Myeloma -- 9.7. Cytogenetic Abnormalities in B and T Cell Lymphomas -- 9.7.1. CLL/SLL -- 9.7.2. Follicular Lymphoma -- 9.7.3. Mantle Cell Lymphoma -- 9.7.4. Marginal Zone Lymphoma -- 9.7.5. Diffuse Large B Cell Lymphoma -- 9.7.6. Burkitt Lymphoma -- 9.7.7. Anaplastic Large Cell Lymphoma -- Key Points -- References -- 10.1. Introduction -- 10.2. Reactive Lymphoid States -- 10.2.1. Viral Lymphadenopathy -- 10.2.2. Bacterial Infections and Lymphadenopathy -- 10.2.3. Toxoplasma gondii and Lymphadenopathy -- 10.2.4. Granulomatous Lymphadenopathy -- 10.2.5. Necrotizing Lymphadenopathy -- 10.2.6. Progressive Transformation of Germinal Centers -- 10.2.7. Regressive Changes in Germinal Centers -- 10.3. Specific Clinical Entities with Lymphadenopathy -- 10.3.1. Kikuchi-Fujimoto Disease -- 10.3.2. Kimura Disease -- 10.3.3. Kawasaki Disease -- 10.3.4. Dermatopathic Lymphadenitis -- 10.3.5. Lymphadenopathy in Autoimmune Diseases -- 10.3.6. Rosai-Dorfman Disease -- 10.3.7. Langerhans Cell Histiocytosis -- 10.3.8. Castleman Disease -- Key Points -- References -- 11.1. Introduction -- 11.2. Follicular Lymphoma -- 11.2.1. Immunophenotyping in Follicular Lymphoma -- 11.2.2. Genetics of Follicular Lymphoma -- 11.3. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma -- 11.3.1. Immunophenotyping for CLL/SLL -- 11.4. B Cell Prolymphocytic Leukemia -- 11.5. Mantle Cell Lymphoma -- 11.6. Marginal Zone B Cell Lymphoma -- 11.6.1. MALT Lymphoma -- 11.6.2. Splenic Marginal Zone Lymphoma -- 11.6.3. Nodal Marginal Zone Lymphoma -- 11.7. Burkitt Lymphoma -- 11.8. Lymphoblastic Leukemia/Lymphoblastic Lymphoma -- 11.9. Lymphoplasmacytic Lymphoma/Waldenstrom Macroglobulinemia -- 11.10. Diffuse Large B Cell Lymphoma -- 11.10.1. B Cell Lymphoma, Unclassifiable with Features Intermediate Between DLBCL and Burkitt Lymphoma (Gray Zone Lymphoma) -- 11.11. Hairy Cell Leukemia -- 11.11.1. Approach to the Diagnosis of Lymphoma -- Key Points -- References -- 12.1. Introduction -- 12.2. Nodal T Cell Lymphomas -- 12.2.1. Angioimmunoblastic T Cell Lymphoma -- 12.2.2. Peripheral T Cell Lymphoma -- 12.2.3. Anaplastic Large Cell Lymphoma -- 12.3. Extranodal NK/T Cell Lymphomas -- 12.3.1. Extranodal NK/T Cell Lymphoma, Nasal Type -- 12.3.2. Enteropathy-associated T Cell Lymphoma -- 12.3.3. Hepatosplenic T Cell Lymphoma -- 12.3.4. Subcutaneous Panniculitis-like T Cell Lymphoma -- 12.4. Cutaneous T Cell Lymphoma -- 12.4.1. Mycosis Fungoides -- 12.4.2. Sezary Syndrome -- 12.4.3. Primary Cutaneous CD30+ T Cell Lymphoproliferative Disease -- 12.5. Leukemia/disseminated -- 12.5.1. T Cell Prolymphocytic Leukemia -- 12.5.2. T Cell Large Granular Lymphocyte Leukemia -- 12.5.3. Chronic Lymphoproliferative Disorders of NK Cells -- 12.5.4. Aggressive NK Cell Leukemia -- 12.5.5. Adult T Cell Leukemia/Lymphoma -- Key Points -- References -- 13.1. Introduction -- 13.2. Overview of Hodgkin Lymphoma -- 13.3. Classification of Hodgkin Lymphoma -- 13.3.1. Nodular Lymphocyte Predominant Hodgkin Lymphoma -- 13.3.2. Classical Hodgkin Lymphoma -- 13.4. Immunostains for Diagnosis of Hodgkin Lymphoma -- 13.5. Staging of Hodgkin Lymphoma -- Key Points -- References -- 14.1. Introduction -- 14.2. Lymphoproliferative Disorders Associated with Immune Deficiency -- 14.2.1. Lymphoproliferative Disorders Associated with Primary Immune Deficiency -- 14.2.2. Lymphoproliferative Disorders Associated with HIV Infection
880-01/(S Machine generated contents note: 1.1. Introduction -- 1.2. Analysis of Various Parameters by Hematology Analyzers -- 1.2.1. RBC Count and Hemoglobin Measurement -- 1.2.2. Hematocrit, Red Blood Cell Distribution Width, Mean Corpuscular Volume, Mean Corpuscular Hemoglobin, and Mean Corpuscular Hemoglobin Concentration -- 1.2.3. Reticulocyte Count -- 1.2.4. WBC Count and Differential -- 1.2.5. Platelet Count, Mean Platelet Volume, and Platelet Differential Width -- 1.3. Review of Peripheral Smear -- 1.3.1. Red Cell Variations and Inclusions -- 1.3.2. WBC Morphology -- 1.3.3. Platelets -- 1.4. Special Situations with CBC and Peripheral Smear Examination -- 1.4.1. Splenic Atrophy or Postsplenectomy -- 1.4.2. Microangiopathic Hemolysis -- 1.4.3. Leukoerythroblastic Blood Picture -- 1.4.4. Parasites, Microorganisms, and Nonhematopoietic Cells in the Peripheral Blood -- 1.4.5. Buffy Coat Preparation -- Key Points -- References -- 2.1. Introduction -- 2.2. Fundamentals of Bone Marrow Examination -- 2.2.1. Dry Tap -- 2.2.2. Granulopoiesis -- 2.2.3. Erythropoiesis -- 2.2.4. Monopoiesis, Megakaryopoiesis, Thrombopoiesis, and Other Cells in Bone Marrow -- 2.3. Bone Marrow Examination Findings and Bone Marrow Failure -- 2.3.1. Disorders of Erythropoiesis, Granulopoiesis, and Thrombopoiesis -- 2.3.2. Infections -- 2.3.3. Granulomatous Changes -- 2.3.4. Storage Disorders -- 2.3.5. Metabolic Bone Diseases -- 2.3.6. Metastatic Tumors -- 2.3.7. Hemophagocytic Syndrome -- 2.3.8. Bone Marrow Necrosis/Infarction -- 2.3.9. Serous Atrophy -- 2.3.10. Bone Marrow Fibrosis -- 2.3.11. Reactive Lymphoid Aggregate -- 2.3.12. Bone Marrow Infiltration in Lymphoproliferative Disorders -- 2.3.13. Amyloidosis -- Key Points -- References -- 3.1. Introduction -- 3.2. Anemia: Morphological and Etiological Classification -- 3.3. Common Causes of Anemia -- 3.3.1. Anemia Due to Blood Loss and Iron Deficiency Anemia -- 3.3.2. Lead Poisoning -- 3.3.3. Anemia of Chronic Disease -- 3.3.4. Sideroblastic Anemia -- 3.3.5. Megaloblastic Anemia -- 3.3.6. Bone Marrow Failure -- 3.3.7. Congenital Dyserythropoietic Anemia -- 3.4. Hemolytic Anemia -- 3.4.1. Hemolytic Anemia Due to Corpuscular Defects -- 3.4.2. Hemolytic Anemia Due to Membrane Defects -- 3.4.3. Hemolytic Anemias Due to Extracorpuscular Defects -- 3.5. Red Cell Poikilocytosis -- 3.6. Red Cell Inclusions -- 3.6.1. Malaria Parasites -- Key Points -- References -- 4.1. Introduction -- 4.2. Hemoglobin Structure and Synthesis -- 4.3. Introduction to Hemoglobinopathies -- 4.3.1. α-Thalassemia -- 4.3.2. β-Thalassemia -- 4.3.3. δ-Thalassemia -- 4.3.4. Sickle Cell Disease -- 4.3.5. Hereditary Persistence of Fetal Hemoglobin -- 4.4. Other Hemoglobin Variants -- 4.5. Laboratory Investigation of Hemoglobinopathies -- 4.5.1. Gel Electrophoresis -- 4.5.2. High-Performance Liquid Chromatography -- 4.5.3. Capillary Electrophoresis -- 4.6. Diagnostic Tips for Thalassemias, Sickle Cell Disease, and Other Hemoglobinopathy -- 4.7. Apparent Hemoglobinopathy After Blood Transfusion -- Key Points -- References -- 5.1. Introduction -- 5.2. Hereditary Variation in White Blood Cell Morphology -- 5.3. Changes in White Cell Counts -- 5.3.1. Neutrophilia -- 5.3.2. Eosinophilia and Monocytosis -- 5.3.3. Basophilia -- 5.3.4. Neutropenia -- 5.3.5. Lymphocytosis and Infectious Mononucleosis -- 5.3.6. Lymphocytopenia -- 5.4. Platelet Disorders -- 5.4.1. Thrombocytopenias -- 5.4.2. Thrombocytosis -- 5.4.3. Thrombocytopathia -- Key Points -- References -- 6.1. Introduction -- 6.2. Classification of Myeloid Neoplasm -- 6.3. Myeloproliferative Neoplasm -- 6.3.1. Chronic Myelogenous Leukemia, BCR-ABL1+ -- 6.3.2. Chronic Neutrophilic Leukemia -- 6.3.3. Polycythemia Vera, Primary Myelofibrosis, and Essential Thrombocythemia -- 6.3.4. Chronic Eosinophilic Leukemia -- 6.3.5. Mastocytosis -- 6.4. Myeloid and Lymphoid Neoplasm Associated with Eosinophilia -- 6.5. Myelodysplastic/Myeloproliferative Neoplasms -- 6.6. Myelodysplastic Syndrome -- 6.6.1. Features of Dysplasia in Red Cells, Erythroid Precursors, Granulocytes, and Megakaryocytes -- 6.6.2. Arriving at a Diagnosis of MDS and Subclassifying MDS -- 6.6.3. Abnormal Localization of Immature Precursors -- 6.6.4. Cytogenetic Abnormalities Associated with MDS -- 6.6.5. Unusual Situations in MDS -- 6.7. Acute Leukemia -- 6.7.1. Blasts -- 6.7.2. Cytochemistry -- 6.7.3. Classification of AML and Diagnosis -- 6.7.4. AML and Flow Cytometry -- 6.7.5. Cytogenetics and AML -- Key Points -- References -- 7.1. Introduction -- 7.2. Diagnostic Approach to Monoclonal Gammopathy Using Electrophoresis -- 7.2.1. Serum Protein Electrophoresis
Note continued: 14.2.3. Post-transplant Lymphoproliferative Disorders -- 14.3. Histiocytic and Dendritic Cell Neoplasms -- 14.3.1. Histiocytic Sarcoma -- 14.3.2. Dendritic Cell Neoplasms -- Key Points -- References -- 15.1. Introduction -- 15.2. Normal Hemostasis -- 15.2.1. Platelets and Platelet Events -- 15.3. Thrombocytopenia and Thrombocytopathia -- 15.3.1. Hereditary Thrombocytopenias -- 15.3.2. Idiopathic Thrombocytopenic Purpura -- 15.3.3. Heparin-induced Thrombocytopenia -- 15.4. Tests for Platelet Function -- 15.4.1. Thromboelastography -- 15.4.2. Platelet Mapping -- 15.5. Secondary Hemostasis -- 15.6. Tests for Secondary Hemostasis -- 15.6.1. Factor Assays -- 15.6.2. Von Willebrand Disease -- 15.6.3. Diagnosis of Various Types of Von Willebrand Disease -- 15.7. Antiplatelets and Anticoagulants -- Key Points -- References -- 16.1. Introduction -- 16.2. Thrombophilia: Inherited Versus Acquired -- 16.3. Factor V Leiden -- 16.3.1. Activated Protein C Resistance Test -- 16.4. Prothrombin Gene Mutation -- 16.5. Protein C Deficiency -- 16.6. Protein S Deficiency -- 16.6.1. Assays for Protein C and Protein S -- 16.7. Antithrombin III Deficiency -- 16.8. Hyperhomocysteinemia -- 16.9. Increased Factor VIII Activity -- 16.10. Acquired Causes of Thrombophilia -- 16.10.1. Lupus Anticoagulant and Anticardiolipin Antibodies -- Key Points -- References -- 17.1. Introduction -- 17.2. Errors in Routine Hematology Testing -- 17.2.1. Errors in Hemoglobin Measurement and RBC Count -- 17.2.2. Errors in MCV and Related Measurements -- 17.2.3. Errors in WBC Counts and WBC Differential Counts -- 17.2.4. Errors in Platelet Count -- 17.3. Errors in Specific Hematology Testing -- 17.3.1. Cold Agglutinins -- 17.3.2. Cryoglobulins -- 17.3.3. Pseudothrombocytopenia -- 17.3.4. Spurious Leukocytosis -- 17.3.5. False-positive Osmotic Fragility Test -- 17.4. Errors in Coagulation Testing -- 17.4.1. Errors in PT and aPTT Measurements -- 17.4.2. Errors in Thrombin Time Measurement -- 17.4.3. Platelet Aggregation Testing with Lipemic, Hemolyzed, or Thrombocytopenic Samples -- 17.4.4. Challenges in Anticoagulants and Lupus Anticoagulant Tests -- Key Points -- References
Bibliography Includes bibliographical references and index
Notes Vendor-supplied metadata
Subject Hematology.
Coagulation.
Blood -- Coagulation.
Hematologic Tests -- methods
Hematologic Diseases -- diagnosis
Blood Coagulation
Hematology
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Blood -- Coagulation
Coagulation
Hematology
Form Electronic book
Author Dasgupta, Amitava, 1958- author.
LC no. 2014946712
ISBN 9780128003817
0128003812