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E-book
Author Barret, Roland, author

Title Medicinal chemistry : fundamentals / Roland Barret
Published London, UK : ISTE Press Ltd ; Oxford, UK : Elsevier Ltd, 2018

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Description 1 online resource
Contents Medicines and drugs -- Importance and evaluation of the pKa -- Importance and evaluation of lipophilicity -- Importance and evaluation of solubility -- Importance and evaluation of the polar surface area (PSA and TPSA) -- Lipinski's rule of five -- Principle of a prodrug -- Pharmacophore -- The European pharmacopoeia
Summary Medicinal Chemistry: Fundaments presents the cycle of the life of drugs, their physico-chemical properties, and consequences that arise in development. The fundamental concepts of Medicinal Chemistry (pharmacophore, prodrugs, Lipinsky rules) are also presented, including discussions on specific concerns of the European Pharmacopeia - the industrialist's bible - its role, and a description of the monographs of active principles
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (EBSCO, viewed July 16, 2018)
Subject Pharmaceutical chemistry.
Pharmacopoeias.
Chemistry, Pharmaceutical
MEDICAL -- Pharmacology.
Pharmaceutical chemistry
Pharmacopoeias
Genre/Form pharmacopoeias.
Pharmacopoeias
Pharmacopoeias.
Pharmacopées.
Form Electronic book
ISBN 9780081027608
0081027605