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Book Cover
Author Carballar-Lejarazu, Rebeca

Title Mosquito Gene Drives and the Malaria Eradication Agenda
Published Milton : Jenny Stanford Publishing, 2023


Description 1 online resource (373 p.)
Summary This book reviews some concepts of gene drive systems and describes pioneering applications to control mosquito populations and prevent parasite transmission
Notes Dr. Rebeca Carballar-Lejarazu's research is focused on insect molecular genetics, vector biology, and the development of synthetic approaches to prevent transmission of mosquito-borne diseases. She has used several genetic strategies such as transposon-based random integration, phiC31 docking-site integration and CRISPR/Cas9 site-specific genome editing technologies to develop transgenic mosquitoes. Dr. Carballar-LejarazĂș is currently working on the development, optimization, and evaluation of a CRISPR/Cas9 gene drive system to engineer mosquitoes that resist malaria parasites (population modification/replacement) in two main malaria African vectors Anopheles gambiae and Anopheles coluzzii. Her insect interests have been centered mainly on vector mosquitoes. However, in 2014, she started a collaboration with Professor Sonqing Wu to study biopesticides to control crop pests in China
Subject Malaria -- Prevention.
Mosquitoes -- Genetic engineering
Gene drives.
MEDICAL / Biostatistics
Gene drives.
Malaria -- Prevention.
Form Electronic book
ISBN 9781000625929