Description |
1 online resource (373 p.) |
Summary |
This book reviews some concepts of gene drive systems and describes pioneering applications to control mosquito populations and prevent parasite transmission |
Notes |
Dr. Rebeca Carballar-Lejarazu's research is focused on insect molecular genetics, vector biology, and the development of synthetic approaches to prevent transmission of mosquito-borne diseases. She has used several genetic strategies such as transposon-based random integration, phiC31 docking-site integration and CRISPR/Cas9 site-specific genome editing technologies to develop transgenic mosquitoes. Dr. Carballar-LejarazĂș is currently working on the development, optimization, and evaluation of a CRISPR/Cas9 gene drive system to engineer mosquitoes that resist malaria parasites (population modification/replacement) in two main malaria African vectors Anopheles gambiae and Anopheles coluzzii. Her insect interests have been centered mainly on vector mosquitoes. However, in 2014, she started a collaboration with Professor Sonqing Wu to study biopesticides to control crop pests in China |
Subject |
Malaria -- Prevention.
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Mosquitoes -- Genetic engineering
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Gene drives.
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MEDICAL / Biostatistics
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Gene drives.
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Malaria -- Prevention.
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Form |
Electronic book
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ISBN |
9781000625929 |
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1000625923 |
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9781003308775 |
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1003308775 |
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9781000626001 |
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1000626008 |
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