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Title Vitamin D : physiology, molecular biology, and clinical applications / edited by Michael F. Holick
Edition 2nd ed
Published [Totowa] : Humana, ©2010

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Description 1 online resource (xxvi, 1155 pages) : illustrations
Series Nutrition and health
Nutrition and health (Totowa, N.J.)
Contents Vitamin D and health: evolution, biologic functions, and recommended dietary intakes for vitamin D -- Photobiology of vitamin D -- The functional metabolism and molecular biology of vitamin D action -- Metabolism and catabolism of vitamin D, its metabolites and clinically relevant analogs -- The molecular biology of the vitamin D receptor -- VDR and RXR subcellular trafficking -- Mechanism of action of 1,25-dihydroxyvitamin D3 on intestinal calcium absorption and renal calcium transport -- Biological and molecular effects of vitamin D on bone -- Biological and molecular effects of vitamin D on the kidney -- Vitamin D and the parathyroids -- Diversity of vitamin D target genes -- Extrarenal synthesis of 1,25-dihydroxyvitamin D and its health implications -- Vitamin D and the innate immunity -- Vitamin D and colon cancer -- Mechanisms of resistance to vitamin D action in human cancer cells -- Vitamin D and the brain: a neuropsychiatric perspective -- Vitamin D modulation of adipocyte function -- Determinants of vitamin D intake -- 25-hydroxybitamin D assays and their clinical utility -- Health disparities and vitamin D -- Vitamin D deficiency in Canada -- Vitamin D deficiency and its health consequences in Northern Europe -- Vitamin D deficiency and consequences for the health of people in Mediterranean countries -- Vitamin D deficiency in the Middle East and its health consequences -- Vitamin D deficiency in the Middle East and its health consequences for adults -- Vitamin D deficiency and its health consequences in Africa -- Vitamin D deficiency and its health consequences in India -- Vitamin D deficiency, rickets, and fluorosis in India -- Vitamin D in Asia
Vitamin D deficiency and its health consequences in New Zealand -- Toxicity of vitamin D -- Vitamin D deficiency in pregnancy and lactation and health consequences -- Vitamin D deficiency in children and its health consequences -- Dietary calcium deficiency and rickets -- Vitamin D in fracture prevention and muscle function and fall prevention -- Inherited defects of vitamin D metabolism -- Molecular defects in the vitamin D receptor associated with hereditary 1,25-dihydroxyvitamin D resistant rickets (HVDRR) -- Receptor-independent vitamin D resistance in subhuman and human primates -- 25-hydroxyvitamin D-1x-hydroxylase: studies in mouse models and implications for human disease -- The health benefits of solar irradiance and vitamin D and the consequences of their deprivation -- Vitamin D status, solar radiation and cancer prognosis -- The epidemiology of vitamin D and cancer risk -- Vitamin D deficiency and the epidemiology of prostate cancer -- Vitamin D for cancer prevention and survival -- The anti-cancer effect of vitamin D: what do the randomized trials show? -- Sunlight, skin cancer, and vitamin D -- Vitamin D and the risk of type 1 diabetes -- Vitamin D and multiple sclerosis -- Vitamin D and type 2 diabetes -- Role of vitamin D for cardiovascular health -- Vitamin D, renin, and blood pressure -- Role of vitamin D and vitamin D analogs for bone health and survival in chronic kidney disease -- Role of vitamin D and ultraviolet radiation in chronic kidney disease -- Role of vitamin D in rheumatoid arthritis -- Vitamin D, respiratory infections, and obstructive airway diseases -- Treatment of immunomediated diseases by vitamin D analogs -- Clinical utility of 1,25-dihydroxyvitamin D3 and it analogues for the treatment of psoriasis -- Affinity alkylating vitamin D analogs as molecular probes and therapeutic agents -- Anti-inflammatory activity of calcitriol that contributes to its therapeutic and chemopreventive effects in prostate cancer
Summary In Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition, leading researchers provide a comprehensive, highly readable overview of the biological functions and clinical applications of vitamin D and its metabolites. Topics range from the most recent recommendations for vitamin D intake to new approaches for the treatment and prevention of vitamin D deficiency and the development of active vitamin D drugs to treat psoriasis and cancer. The book demonstrates the significant role that vitamin D has in maintaining good bone health and the prevention of osteoporosis, a
Analysis celbiologie
cellular biology
biochemie
biochemistry
geneeskunde
medicine
endocrinologie
endocrinology
voeding
nutrition
klinische voeding
clinical nutrition
volksgezondheid
public health
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes English
Print version record
In Springer eBooks
Subject Vitamin D -- Physiological effect
Vitamin D -- Therapeutic use
Vitamin D deficiency.
Biochemistry.
Vitamin D -- physiology
Vitamin D -- pharmacology
Vitamin D -- therapeutic use
Vitamin D Deficiency
Biochemistry
biochemistry.
Médecine.
Vitamin D deficiency
Vitamin D -- Physiological effect
Vitamin D -- Therapeutic use
Form Electronic book
Author Holick, M. F. (Michael F.)
ISBN 9781603273039
1603273034
1280692065
9781280692062
9786613669001
6613669008