| Description |
1 online resource |
| Contents |
880-01 Front Cover; STUDIES ON HEPATITIS VIRUSES; STUDIES ON HEPATITIS VIRUSES: Life Cycle, Structure, Functions, and Inhibition; Copyright; Dedication; CONTENTS; ABOUT THE AUTHOR; PREFACE; 1 -- Viral Hepatitis: Historical Perspective, Etiology, Epidemiology, and Pathophysiology; 1. INTRODUCTION; 2. ETIOLOGY OF INFECTION; 2.1 Hepatitis A Virus; 2.2 Hepatitis B Virus; 2.3 Hepatitis C Virus; 2.4 Hepatitis D Virus; 2.5 Hepatitis E Virus; 3. EPIDEMIOLOGY; 3.1 Hepatitis A; 3.2 Hepatitis B; 3.3 Hepatitis C; 3.4 Hepatitis D; 3.5 Hepatitis E; 4. PATHOPHYSIOLOGY; 4.1 Hepatitis A; 4.2 Hepatitis B |
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880-01/(S 2.1.4 Pseudoxazolones2.1.5 Serine and Threonine β-Lactones; 2.1.6 Heteroaromatic Esters; 2.2 Theoretical; 3. ANTI-HDV DRUGS STUDIES; 3.1 Experimental; 3.2 Theoretical; 4. ANTI-HEV DRUGS STUDIES; 4.1 Experimental; 4.2 Theoretical; 5. CONCLUSIONS; REFERENCES; FURTHER READING; 6 -- The Medicinal Chemistry of Antihepatitis Agents II: Anti-HBV Agents; 1. INTRODUCTION; 2. EXPERIMENTAL STUDIES; 2.1 Drugs Acting Against DNA Synthesis; 2.1.1 Nucleosides; 2.1.2 Indoles; 2.1.3 Benzimidazoles; 2.1.4 Thiazolides; 2.1.5 Matijing-Su Derivatives; 2.2 Anti-HBsAg and Anti-HBeAg Agents; 2.2.1 Lignan Derivatives |
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4.3 Hepatitis C4.4 Hepatitis D; 4.5 Hepatitis E; 5. CONCLUSIONS; REFERENCES; 2 -- Hepatitis Viruses: Structure and Replication; 1. INTRODUCTION; 2. STRUCTURE AND REPLICATION OF HEPATITIS VIRUSES; 2.1 Hepatitis A Virus; 2.1.1 Structure; 2.1.2 Replication; 2.2 Hepatitis B Virus; 2.2.1 Structure; 2.2.2 Replication; 2.3 Hepatitis C Virus; 2.3.1 Structure; 2.3.2 Replication; 2.4 Hepatitis D Virus; 2.4.1 Structure; 2.4.2 Replication; 2.5 Hepatitis E Virus; 2.5.1 Structure; 2.5.2 Replication; 3. CONCLUSIONS; REFERENCES; FURTHER READING |
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3 -- Inhibition of Viruses: Promising Targets and Their Importance1. INTRODUCTION; 2. POLYMERASES; 3. PROTEASES; 3.1 Capsid Proteins; 3.2 Viral Proteins; 3.3 Viroporins; 3.4 Other Proteins; 4. IMPORTANT DRUG TARGETS IN HEPATITIS VIRUSES; 4.1 Hepatitis A Virus; 4.1.1 3C Protease; 4.1.2 2B Protease; 4.2 Hepatitis B Virus; 4.2.1 Antigens; 4.2.2 Hepatitis B Virus Polymerase; 4.3 Hepatitis C Virus; 4.3.1 NS3/4A Protease; 4.3.2 NS4B Protease; 4.3.3 NS5A Protease; 4.3.4 NS5B Polymerase; 4.4 Hepatitis Delta Virus; 4.5 Hepatitis E Virus; 5. CONCLUSIONS; REFERENCES; FURTHER READING |
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4 -- Hepatitis Therapy: Present Status1. INTRODUCTION; 1.1 Hepatitis A Virus; 1.2 Hepatitis B Virus; 1.3 Hepatitis C Virus; 1.4 Hepatitis D Virus; 1.5 Hepatitis E Virus; 2. TREATMENT OF HEPATITIS; 3. HEPATITIS THERAPIES; 3.1 Hepatitis A; 3.2 Hepatitis B and C; 3.3 Hepatitis D; 3.4 Hepatitis E; 4. CONCLUSIONS; REFERENCES; 5 -- The Medicinal Chemistry of Antihepatitis Agents I: Anti-HAV, Anti-HDV, and Anti-HEV Agents; 1. INTRODUCTION; 2. ANTI-HAV DRUGS STUDIES; 2.1 Experimental; 2.1.1 Peptide Aldehyde Inhibitors; 2.1.2 AzaGlutamine and Keto-Glutamine Derivatives; 2.1.3 Azodicarboxamides |
| Summary |
Studies on Hepatitis Viruses: Life Cycle, Structure, Functions, and Inhibition presents the latest on this systemic infection that predominantly affects the liver with inflammation that can be acute or chronic. Hepatitis viruses have been the subject of intense study in the last twenty years, with a wealth of information related to their lifecycle, structure, functions and inhibition being presented. This book compiles the most important developments and research, giving users a very useful guide on this evolving area of virology and medicinal chemistry |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (EBSCO, viewed June 26, 2018) |
| Subject |
Hepatitis viruses.
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Hepatitis Viruses -- physiology
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Hepatitis, Viral, Human -- virology
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Hepatitis Viruses
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Hepatitis viruses
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| Form |
Electronic book
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| ISBN |
9780128133316 |
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0128133317 |
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