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Book Cover
Author Vanhoutte, Paul M

Title Edhf 2002 : Proceedings of the 4th International Symposium on Endothelium-Dependent Hyperpolarizations
Published Baton Rouge : CRC Press, 2005


Description 1 online resource (454 pages)
Contents Book Cover -- Title -- Copyright -- Contents -- Preface -- Acknowledgements -- Contributors -- 1 Potassium channels and membrane potential in vascular endothelial and smooth muscle cells -- 2 Possible contribution of CLCA1 to calcium-activated chloride channels in murine smooth muscle cells -- 3 Trafficking and transduction functions of the Na pump in vascular smooth muscle cells -- 4 Isoforms of the Na, K-ATPase -- 5 Calcium sparks and membrane potential -- 6 Proteinase-activated receptor-2: release of an endothelium-derived hyperpolarizing factor distinct from that released by -- 7 Mechanical stimulation increases the activity and expression of cytochrome P450 2C in porcine coronary artery endothelial -- 8 Important role of hydrogen peroxide as an endothelium-derived hyperpolarizing factor in animals and humans -- 9 Altered calcium dynamics do not account for the attenuation of EDHF-mediated dilatations in the middle cerebral artery of -- 10 Connexin-mimetic peptides: influence on nitric oxide synthase-and cyclooxygenase-independent renal vasodilatation, basal -- 11 Urocortin-induced relaxations of the rat coronary artery -- 12 Nitric oxide is the only EDHF released by the endothelium in lymphatic vessels of the guinea-pig mesentery -- 13 Role of EDHF in vascular tone in vivo -- 14 Endothelium-derived hyperpolarizing factor, myoendothelial gap junctions and hypertension -- 15 Improvement of age-related impairment of endothelium-dependent hyperpolarization by renin-angiotensin system blockade -- 16 Characterization of endothelium-derived hyperpolarizing factor-mediated relaxation of small mesenteric arteries from -- 17 Endothelium-dependent responses in small arteries isolated from normal and pre-eclamptic pregnant women -- 18 Free radical species and endothelium dysfunction during deoxycorticosterone-salt induced hypertension
19 EDHF involvement in skin pressure-induced vasodilatation -- 20 N-acetylcysteine and immobilization stress attenuate dysregulation of the endothelium-dependent coronary vascular tone -- 21 Red wine polyphenolic compounds induce EDHF-mediated relaxation and hyperpolarization in the porcine coronary artery: -- 22 Estrogen substitution restores the basal influence of nitric oxide and endothelium-derived hyperpolarizing factor on -- 23 Ascorbate inhibits EDHF in the bovine eye but not in the porcine coronary artery -- 24 Gabexate mesilate inhibits endothelium-dependent relaxation, but causes endothelium-independent relaxation of rat blood -- 25 Mechanisms underlying basal vascular tone in the guinea-pig mesenteric arterioles -- 26 Endothelium-dependent depolarization and its implications for endothelium-derived hyperpolarizing factor -- 27 Role of gap junctions in EDHF-mediated relaxation response in human subcutaneous resistance arteries -- 28 Permissive role of cAMP in the mediation of relaxations initiated by endothelial hyperpolarization -- 29 Myoendothelial gap junctions-the critical link for endothelium-derived hyperpolarizing factor -- 30 Longitudinal spread of agonist-evoked hyperpolarization in the rat mesenteric artery -- 31 Effect of HEPES on EDHF responses in porcine coronary and rat mesenteric arteries -- 32 Quantification of the amount of potassium released by cultured porcine coronary endothelial cells, stimulated by bradykinin -- 33 The intensity of agonist-stimulation influences the mechanism for relaxation in rat mesenteric arteries -- 34 Small and intermediate conductance Ca 2-activated K channels (SKCa and IK) in porcine coronary endothelium: -- 35 The role of KCa in endothelial cell hyperpolarization and endothelium-dependent relaxation in the rabbit aorta
36 The contribution of D-tubocurarine and apamin-sensitive potassium channels to endothelium-derived hyperpolarizing factor -- 37 Ouabain blocks EDNO-mediated relaxation in mesenteric veins and EDHF-mediated relaxation in mesenteric arteries of the -- 38 Inhibitors of EDHF-evoked responses and the calcium signal in endothelial cell of mesenteric artery -- 39 Roles of the inward-rectifier K channel and Na K -ATPase in the hyperpolarization to K in rat mesenteric arteries -- 40 Importance of intracellular concentration of sodium in the relaxation of rat isolated mesenteric arteries by potassium -- 41 Inhibition of bradykinin-induced relaxations by an epoxyeicosatrienoic acid antagonist:14,15-epoxyeicosa- 5Z-monoenoic -- 42 Local release of EDHF initiates a conducted dilatation, but is not the upstream mediator in arterioles of the hamster -- 43 Interaction of astrocytes and cerebral endothelial cells: function of astrocytic epoxyeicosatrienoic acids in the -- 44 11,12-EETs hyperpolarize human platelets -- 45 Epoxyeicosatrienoic acid activates cloned BKCa channel subunit through ADP-ribosylation of the G-protein -- 46 Different role of epoxyeicosatrienoic acids (EET11,12) in EDHF-mediated relaxation in small porcine coronary and pulmonar -- 47 EDHF 2002: the take home message -- References -- Index
Summary Understanding the nature and role of endothelium-derived hyperpolarizing factor appears to be crucial in the quest for improved treatments for hypertension, diabetes, ischemia-reperfusion and other vascular disorders. EDHF 2002 contains the proceedings of the Fourth International Symposium on endothelium-dependent hyperpolarizations and will be of interest not only to physiologists and pharmacologists puzzled by the complexity of the interactions between the endothelium and underlying vascular smooth muscle cells, but also clinical researchers and physicians treating patients with cardiovascular diseases
Notes Publisher supplied metadata and other sources
Subject Vascular endothelium -- Physiology -- Congresses
Vascular endothelium -- Physiology
Genre/Form Conference papers and proceedings
Form Electronic book
ISBN 9780203987360