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Title Prevention of type 2 diabetes : from science to therapy / Derek LeRoith, editor
Published New York, NY : Springer, ©2012

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Description 1 online resource (xiii, 259 pages)
Contents 880-01 Prevention of Type 2 Diabetes; from Science to Therapies / Emily Jane Gallagher and Derek LeRoith -- Pathophysiology: Loss of [beta]-Cell Function / Ele Ferrannini and Andrea Mari -- Pathophysiology of Insulin Resistance: Implications for Prevention / Shamsa Ali and Vivian A. Fonseca -- Epidemiology Including Youth Through Adulthood and Socioeconomic Impact / Helen Looker -- Prediabetes Genes in Pima and Amish / Leslie J. Baier -- Predicting Diabetes / Rachel Dankner and Jesse Roth -- Screening for Prediabetes and Diabetes / Amir Tirosh -- Neuropathy in Prediabetes and the Metabolic Syndrome / Aaron I. Vinik and Marie-Laure Nevoret -- Interventional Trials to Prevent Diabetes: Diabetes Prevention Program / Vanita R. Aroda and Robert E. Ratner -- Decreasing Postprandial Plasma Glucose Using an [alpha]-Glucosidase Inhibitor in Subjects with IGT for the Prevention of Type 2 Diabetes Mellitus: The STOP-NIDDM Trial / Jean-Louis Chiasson, Markku Laakso and Markolf Hanefeld -- Da Qing, Finnish DPP, Tripod, and Dream: Lifestyle and Thiazolidinediones in the Prevention of Diabetes / Mariela Glandt and Zachary Bloomgarden -- Community Approaches to Diabetes Prevention / Ann Albright and David Williamson -- Think Locally, Act Locally, Extend Globally: Diabetes Prevention Through Partnerships with Local Communities / Carol R. Horowitz and Brett Ives -- Global Challenge in Diabetes Prevention from Practice to Public Health / Peter E.H. Schwarz
880-01/(S 01. Prevention of Type 2 Diabetes; from Science to Therapies: Introduction -- 02. Pathophysiology: Loss of ß-cell function -- 03. Pathophysiology of Insulin Resistance: Implications for Prevention -- 04. Epidemiology Including Youth through Adulthood & Socioeconomic Impact.- 05. Prediabetes Genes in Pima and Amish -- 06. Predicting Diabetes -- 07. Screening for Prediabetes and Diabetes -- 08. Neuropathy in pre-Diabetes and the Metabolic Syndrome -- 09. Interventional Trials to Prevent Diabetes: Diabetes Prevention Program.- 10. Decreasing Postprandial Plasma Glucose in Subjects with IGT by Using an α (alpha)-Glucosidase Inhibitor for the Prevention of Type 2 Diabetes Mellitus: The STOP-NIDDM Trial.-11. Da Qing, Finnish DPP, Tripod and Dream: Lifestyle and Thiazolidinediones in the Prevention of Diabetes.- 12.Community Approaches to Diabetes Prevention -- 13. Think Locally, Act Locally, Extend Globally: Diabetes Prevention Through Partnerships with Local Communities.- 14. Global Challenge in Diabetes Prevention from Practice to Public Health
Summary There is a world-wide epidemic on obesity. This epidemic is driving the immense proportions of Type 2 diabetes across the globe. While there are numerous therapies for treating Type 2 diabetes, the most effective therapy is prevention. Prevention of Type 2 diabetes can be achieved properly by simultaneous prevention of obesity. Prediabetes, or metabolic syndrome, is the period between simple obesity and diabetes, and this critical period needs to be identified in a more consistent and systematic manner by clinicians worldwide. Clinical trials have indicated that diabetes prevention can be achieved by lifestyle changes and also by certain medications, though none are yet approved for use in prevention. On the other hand, there are funding agencies such as the NIH, CDC, and State Institutions that are interested in studying the prevention paradigms in different communities and ethnic minorities who are most prone to this epidemic. For these reasons, this title by renowned physician-scientist Derek LeRoith is both timely and vitally important for academic physicians, practitioners, allied health care providers, analysts, community activists, and all others interested in this increasing epidemic. This book provides a unique and comprehensive synthesis of the prevention and early diagnosis of Type 2 Diabetes, focusing on identifying risk factors and then moving into topics that address how to prevent their progression to full-blown diabetes. The difficult task of changing patients' behavior is given special emphasis. The chapters in this practical volume are written by a wide range of international experts, refelecting the editor's distinguished, internationally renowned career. The volume is organized in eight sections: an introduction to the overall issue of prevention, definitions of values based on ADA guidelines, pathophysiology, discussion of a range of interventional trials regarding prevention, and an overview of state-of-the-art clinical management approaches. Comprehensive and timely, Prevention of Type 2 Diabetes: From Science to Therapy is an essential reference for those treating and researching Type 2 Diabetes
Analysis Medicine
Family medicine
Internal medicine
Endocrinology
Medicine & Public Health
General Practice / Family Medicine
Bibliography Includes bibliographical references and index
Subject Type 2 diabetes -- Prevention
Prediabetic State -- prevention & control
Primary Prevention -- methods
Diabetes Mellitus, Type 2 -- physiopathology
Diabetes Mellitus, Type 2 -- prevention & control
Diabetes Complications -- prevention & control
HEALTH & FITNESS -- Diseases -- Diabetes.
Médecine.
Type 2 diabetes -- Prevention.
Form Electronic book
Author LeRoith, Derek, 1945-
ISBN 9781461433149
1461433142
1461433134
9781461433132
9781461485469
1461485460