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Tumor Microenvironments -- See Tumor Microenvironment


The milieu surrounding neoplasms consisting of cells, vessels, soluble factors, and molecules, that can influence and be influenced by, the neoplasm's growth
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Tumor, Myocardial (Rhabdomyomas and Fibromas) -- See Heart Neoplasms


Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM
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Tumor Necrosis Factor -- See Tumor Necrosis Factor-alpha


Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS
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Tumor necrosis factor.   9
Tumor necrosis factor -- Agonists -- Therapeutic use : Therapeutic targets of the TNF superfamily / edited by Iqbal S. Grewal  2009 1
Tumor Necrosis Factor-alpha : Tumor necrosis factor : methods and protocols / edited by Angelo Corti and Pietro Ghezzi  2004 1
Tumor Necrosis Factor-alpha -- antagonists & inhibitors : TNF-alpha inhibitors / edited by J.M. Weinberg and R. Buchholz  2006 1
Tumor Necrosis Factor-alpha -- therapeutic use : The handbook of biological therapy : a guide to the use and safety of biological therapies in rheumatology, dermatology, and gastroenterology / Bruce Kirkham [and others]  2008 1
Tumor necrosis factor -- Congresses : Advances in TNF family research : proceedings of the 12th International TNF Conference, 2009 / David Wallach, Andrew Kovalenko, Marc Feldmann, editors  2011 1
Tumor necrosis factor -- Inhibitors   4
Tumor necrosis factor -- Laboratory manuals   2
 

Tumor Necrosis Factor Ligand Superfamily Member 2 -- See Tumor Necrosis Factor-alpha


Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS
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Tumor necrosis factor -- Pathophysiology : TNF pathophysiology : molecular and cellular mechanisms / volume editors, G. Kollias, P.P. Sfikakis  2010 1
Tumor necrosis factor -- Physiological effect : Death receptors and cognate ligands in cancer / Holger Kalthoff, ed  2009 1
 

Tumor Necrosis Factor Receptor -- See Receptors, Tumor Necrosis Factor


Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells
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Tumor Necrosis Factor Receptor-Associated Peptides and Proteins -- physiology : TNF receptor associated factors (TRAFs) / edited by Hao Wu  2007 1
 

Tumor Necrosis Factor Receptor Superfamily, Member 6 -- See fas Receptor


A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome
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Tumor Necrosis Factor Receptor Superfamily, Member 9 -- immunology : CD137 pathway : immunology and diseases / edited by Lieping Chen  2006 1
 

Tumor Necrosis Factor Receptor Superfamily, Member 10 -- See Receptors, TNF-Related Apoptosis-Inducing Ligand


Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM
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Tumor Necrosis Factor Receptor Superfamily, Member 10a -- See Receptors, TNF-Related Apoptosis-Inducing Ligand


Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM
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Tumor Necrosis Factor Receptor Superfamily, Member 10b -- See Receptors, TNF-Related Apoptosis-Inducing Ligand


Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM
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Tumor Necrosis Factor Receptors -- See Receptors, Tumor Necrosis Factor


Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells
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Tumor necrosis factor -- Receptors   6
Tumor necrosis factor -- Receptors -- Laboratory manuals : CD95 : methods and protocols / edited by Patrick Legembre  2017 1
Tumor necrosis factor -- Receptors -- Physiological effect : Death receptors and cognate ligands in cancer / Holger Kalthoff, ed  2009 1
 

Tumor Necrosis Factor Superfamily Ligands -- See Tumor Necrosis Factors


A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS
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Tumor necrosis factor -- Therapeutic use : Tumor necrosis factor / Toma P. Rossard, editor  2009 1
Tumor Necrosis Factors   3
Tumor Necrosis Factors -- genetics : Tumor necrosis factor / Toma P. Rossard, editor  2009 1
Tumor Necrosis Factors -- immunology : TNF pathophysiology : molecular and cellular mechanisms / volume editors, G. Kollias, P.P. Sfikakis  2010 1
Tumor Necrosis Factors -- metabolism   3
Tumor Necrosis Factors -- physiology   4
Tumor Necrosis Factors -- therapeutic use : Therapeutic targets of the TNF superfamily / edited by Iqbal S. Grewal  2009 1
Tumor-Nekrose-Faktor : Death receptors and cognate ligands in cancer / Holger Kalthoff, ed  2009 1
 

Tumor, Nervous System -- See Nervous System Neoplasms


Benign and malignant neoplastic processes arising from or involving components of the central, peripheral, and autonomic nervous systems, cranial nerves, and meninges. Included in this category are primary and metastatic nervous system neoplasms
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Tumor, Neuroendocrine -- See Neuroendocrine Tumors


Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition
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Tumor of Rete Testis -- See Testicular Neoplasms


Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms
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Tumor, Osteosarcoma -- See Osteosarcoma


A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
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Tumor, Peripheral Nerve -- See Peripheral Nervous System Neoplasms


Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)
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Tumor, Pineal -- See Pinealoma


Neoplasms which originate from pineal parenchymal cells that tend to enlarge the gland and be locally invasive. The two major forms are pineocytoma and the more malignant pineoblastoma. Pineocytomas have moderate cellularity and tend to form rosette patterns. Pineoblastomas are highly cellular tumors containing small, poorly differentiated cells. These tumors occasionally seed the neuroaxis or cause obstructive HYDROCEPHALUS or Parinaud's syndrome. GERMINOMA; CARCINOMA, EMBRYONAL; GLIOMA; and other neoplasms may arise in the pineal region with germinoma being the most common pineal region tumor. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2064; Adams et al., Principles of Neurology, 6th ed, p670)
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Tumor, Pineal Gland -- See Pinealoma


Neoplasms which originate from pineal parenchymal cells that tend to enlarge the gland and be locally invasive. The two major forms are pineocytoma and the more malignant pineoblastoma. Pineocytomas have moderate cellularity and tend to form rosette patterns. Pineoblastomas are highly cellular tumors containing small, poorly differentiated cells. These tumors occasionally seed the neuroaxis or cause obstructive HYDROCEPHALUS or Parinaud's syndrome. GERMINOMA; CARCINOMA, EMBRYONAL; GLIOMA; and other neoplasms may arise in the pineal region with germinoma being the most common pineal region tumor. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2064; Adams et al., Principles of Neurology, 6th ed, p670)
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Tumor, Pineal Parenchymal -- See Pinealoma


Neoplasms which originate from pineal parenchymal cells that tend to enlarge the gland and be locally invasive. The two major forms are pineocytoma and the more malignant pineoblastoma. Pineocytomas have moderate cellularity and tend to form rosette patterns. Pineoblastomas are highly cellular tumors containing small, poorly differentiated cells. These tumors occasionally seed the neuroaxis or cause obstructive HYDROCEPHALUS or Parinaud's syndrome. GERMINOMA; CARCINOMA, EMBRYONAL; GLIOMA; and other neoplasms may arise in the pineal region with germinoma being the most common pineal region tumor. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2064; Adams et al., Principles of Neurology, 6th ed, p670)
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Tumor, Pituitary -- See Pituitary Neoplasms


Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA
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Tumor, Plasma Cell -- See Plasmacytoma


Any discrete, presumably solitary, mass of neoplastic PLASMA CELLS either in BONE MARROW or various extramedullary sites
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Tumor progression -- See Cancer invasiveness


Here are entered works on the ability of cancer to infiltrate and actively destroy surrounding tissue. Works on the transfer of cancer to an organ or part of the body remote from the primary site are entered under Metastasis
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Tumor Promoters -- See Carcinogens


Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included
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Tumor promotion -- See Cocarcinogenesis


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  Tumor proteins -- 4 Related Subjects   4
Tumor proteins.   7
 

Tumor, Rectal -- See Rectal Neoplasms


Tumors or cancer of the RECTUM
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