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Title Tumor microenvironment and cellular stress : signaling, metabolism, imaging, and therapeutic targets / Constantinos Koumenis, Ester Hammond, Amato Giaccia, editors
Published New York : Springer, 2014

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Description 1 online resource
Series Advances in experimental medicine and biology ; volume 772
Advances in experimental medicine and biology ; v. 772.
Contents Hypoxia and Metabolism in Cancer / Karim Bensaad and Adrian L. Harris -- Hypoxia and Regulation of Cancer Cell Stemness / Zhong Yun and Qun Lin -- Hypoxia-Mediated Metastasis / Joan Chang and Janine Erler -- Escape Mechanisms from Antiangiogenic Therapy: An Immune Cell's Perspective / Lee Rivera, Melissa Pandika and Gabriele Bergers -- Hypoxic VDAC1: A Potential Mitochondrial Marker for Cancer Therapy / M. Christiane Brahimi-Horn and N.M. Mazure -- Hypoxia-Directed Drug Strategies to Target the Tumor Microenvironment / Michael P. Hay, Kevin O. Hicks and Jingli Wang -- Radiotherapy and the Tumor Microenvironment: Mutual Influence and Clinical Implications / Reid F. Thompson and Amit Maity -- Autophagy and Cell Death to Target Cancer Cells: Exploiting Synthetic Lethality as Cancer Therapies / Julie Reyjal, Kevin Cormier and Sandra Turcotte -- Intratumoral Hypoxia as the Genesis of Genetic Instability and Clinical Prognosis in Prostate Cancer / Daria Taiakina, Alan Dal Pra and Robert G. Bristow -- miR-210: Fine-Tuning the Hypoxic Response / Mircea Ivan and Xin Huang -- The Role of Complement in Tumor Growth / Ruben Pio, Leticia Corrales and John D. Lambris -- Imaging Angiogenesis, Inflammation, and Metastasis in the Tumor Microenvironment with Magnetic Resonance Imaging / S├ębastien Serres, Emma R. O'Brien and Nicola R. Sibson
Hypoxia and metabolism in cancer -- Hypoxia and Regulation of Cancer Cell Stemness -- Hypoxia-mediated metastasis -- Escape Mechanisms from Antiangiogenic Therapy: An Immune Cells Perspective -- Hypoxic VDAC1: a potential mitochondrial marker for cancer therapy -- Hypoxia directed drug strategies to target the tumor microenvironment -- Radiotherapy and the Tumor Microenvironment: Mutual Influence and Clinical Implications -- Autophagy and cell death to target cancer cells: exploiting synthetic lethality as cancer therapeutic -- Intratumoral Hypoxia as the Genesis of Genetic Instability and Clinical Prognosis in Prostate Cancer -- miR-210: Fine-Tuning the Hypoxic Response -- The role of complement in tumor growth -- Imaging angiogenesis, inflammation and metastasis in the tumor microenvironment with magnetic resonance imaging
Summary The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery
Notes Includes index
Bibliography Includes bibliographical references and index
Notes English
Print version record
In Springer eBooks
Subject Tumors.
Pathology, Cellular.
Stress (Physiology)
Stress (Psychology)
Microbiology.
Tumor Microenvironment -- physiology
Cell Survival
Neoplasms
Stress, Physiological
Stress, Psychological
Microbiology
microbiology.
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Stress (Psychology)
Pathology, Cellular
Stress (Physiology)
Tumors
Form Electronic book
Author Koumenis, Constantinos, editor
Hammond, Ester, editor
Giaccia, Amato J., editor
ISBN 9781461459156
146145915X
1461459141
9781461459149