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E-book

Title Neglected diseases and drug discovery / edited by Michael J. Palmer, Timothy N.C. Wells
Published [Cambridge, U.K.] : Royal Society of Chemistry, [2011], ©2012

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Description 1 online resource (xix, 438 pages) : illustrations
Series RSC drug discovery series, 2041-3203 ; no. 14
RSC drug discovery series ; 14.
Contents Malaria; Trypanosomatids; TB; Flavivirus based diseases (Dengue fever, Yellow fever, West Nile virus); Helminth, nematode and schistosoma based diseases; HIV Lower respiratory tract infection; Diarrhea
Summary There are about 8 million deaths each year from neglected tropical diseases (NTDs) in the underdeveloped world, whilst drug discovery focus and practice is only recently taking on greater urgency and embracing the latest technologies. This unique book is a state of the art review of drug discovery in respect of NTDs and highlights best practice to guide the ongoing drug discovery effort and also to raise debate and awareness in areas that remain highly neglected. All the major diseases such as malaria, trypanosomatids and TB are covered, with a review of each disease and established compounds, new mechanistic classes and new horizons. Each chapter highlights the key science that has led to breakthroughs, with detailed assessment of the key medicinal chemistry involved, and critical appraisal of new emerging approaches. Later chapters highlight under publicized disease areas where the medical needs are neglected and research is very limited, to raise awareness. The editors, acknowledged experts in the field, have a wealth of experience in successful drug discovery practice and tropical diseases
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Tropical medicine -- Developing countries
Drug development.
Tropical medicine.
Neglected Diseases -- prevention & control
Developing Countries
Drug Discovery
Tropical Medicine
Chemistry.
MEDICAL -- Drug Guides.
MEDICAL -- Nursing -- Pharmacology.
MEDICAL -- Pharmacology.
MEDICAL -- Pharmacy.
Drug development
Tropical medicine
Developing countries
Form Electronic book
Author Palmer, Mike.
Wells, Timothy N. C.
ISBN 9781849733496
184973349X
1849731926
9781849731928