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Title TRP ion channel function in sensory transduction and cellular signaling cascades / edited by Wolfgang B. Liedtke with Stefan Heller
Published Boca Raton : CRC/Taylor & Francis, ©2007


Description 1 online resource (1 electronic resource) : illustrations
Series Frontiers in neuroscience
Frontiers in neuroscience (Boca Raton, Fla.)
Contents Front Cover; Series Preface; Preface; The Editors; Contributors; Abstract; Contents; Chapter 1. The TRPC Family of Ion Channels: Relation to the TRP Superfamily and Role in Receptor- and Store- Operated Calcium Entry; Chapter 2. Multiple Mechanisms of TRPC Activation; Chapter 3. TRPC2 and the Molecular Biology of Pheromone Detection in Mammals; Chapter 4. TRP Channels and Axon Pathfinding; Chapter 5. TRPV1 Receptors and Signal Transduction; Chapter 6. Complex Regulation of TRPV1 by Vanilloids; Chapter 7. TRPV2: A Calcium- Permeable Cation Channel Regulated by Insulin-Like Growth Factors
Chapter 8. Molecular Mechanisms of TRPV4 GatingChapter 9. TRPV4: A Multifunctional Nonselective Cation Channel with Complex Regulation; Chapter 10. TRPV4 and TRPM3 as Volume-Regulated Cation Channels; Chapter 11. TRPA1:A Sensory Channel of Many Talents; Chapter 12. TRPA1 in Auditory and Nociceptive Organs; Chapter 13. TRPM8: The Cold and Menthol Receptor; Chapter 14. Activation Mechanisms and Functional Roles of TRPP2 Cation Channels; Chapter 15. The Ca2+-Activated TRP Channels: TRPM4 and TRPM5; Chapter 16. Genetics Can Be Painless: Molecular Genetic Analysis of Nociception in Drosophila
Chapter 17. TRPV Family Ion Channels and Other Molecular Components Required for Hearing and Proprioception in Drosophila Chapter 18. The TRPV Channel in C. elegans Serotonergic Neurons; Chapter 19. TRP Channel Functioning in Mating and Fertilization; Chapter 20. The Role of TRP Channels in Thermosensation; Chapter 21. Voltage and Temperature Gating of ThermoTRP Channels; Chapter 22. TRPV Channels' Function in Osmo- and Mechanotransduction; Chapter 23. TRP Channel Trafficking; Chapter 24. Protein-Protein Interactions in TRPC Channel Complexes
Chapter 25. Structural Insights into the Function of TRP Channels Chapter 26. Functional Significance of Transient Receptor Potential Channels in Vascular Function; Chapter 27. Role of TRPV4 in the Mechanotransduction of Shear Stress in Endothelial Cells; Chapter 28. A New Insight into the Function of TRPV2 in Circulatory Organs; Chapter 29. The Role of TRPV4 in the Kidney; Chapter 30. The TRPV4 Channel in Ciliatd Epithelia; Chapter 31. Protease-Activated Receptors: Mechanisms by Which Proteases Sensitize TRPV Channels to Induce Neurogenic Inflannation and Pain; Index; Back Cover
Summary Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of stimuli from both within and outside the cell body. How we sense heat and cold, how we taste food, how eggs are fertilized, how the heart expands and contracts is each dependent on the function of these channels. While no single book could
Notes Title from resource home page (NCBI Bookshelf, viewed October 19, 2009)
Bibliography Includes bibliographical references
Notes English
Subject TRP channels.
Ion Channels -- physiology
Transient Receptor Potential Channels -- physiology
Transient Receptor Potential Channels
Sensory Receptor Cells -- physiology
Signal Transduction -- physiology
SCIENCE -- Life Sciences -- Biochemistry.
TRP channels
Form Electronic book
Author Liedtke, Wolfgang B
Heller, Stefan
ISBN 9781420005844