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Title Transient receptor potential (TRP) channels / contributors: J. Abramowitz [and others] ; editors, Veit Flockerzi and Bernd Nilius
Published Berlin ; New York : Springer, ©2007


Description 1 online resource (xiv, 622 pages) : illustrations (some color)
Series Handbook of experimental pharmacology, 0171-2004 ; v. 179
Handbook of experimental pharmacology ; v. 179. 0171-2004
Contents An Introduction on TRP Channels -- An Introduction on TRP Channels -- TRPC Channel Subfamily -- TRPC1 Ca2+-Permeable Channels in Animal Cells -- TRPC2: Molecular Biology and Functional Importance -- TRPC3: A Multifunctional, Pore-Forming Signalling Molecule -- Ionic Channels Formed by TRPC4 -- Canonical Transient Receptor Potential 5 -- TRPC6 -- TRPC7 -- TRPV Channel Subfamily -- Capsaicin Receptor: TRPV1 A Promiscuous TRP Channel -- 2-Aminoethoxydiphenyl Borate as a Common Activator of TRPV1, TRPV2, and TRPV3 Channels -- TRPV4 -- TRPV5, the Gateway to Ca2+ Homeostasis -- TRPV6 -- TRPM Channel Subfamily -- TRPM2 -- TRPM3 -- Insights into TRPM4 Function, Regulation and Physiological Role -- TRPM5 and Taste Transduction -- TRPM6: A Janus-Like Protein -- The Mg2+ and Mg2+-Nucleotide-Regulated Channel-Kinase TRPM7 -- TRPM8 -- Other TRP Channels -- TRPA1 -- TRPP2 Channel Regulation -- TRP Proteins and Specific Cellular Functions -- Know Thy Neighbor: A Survey of Diseases and Complex Syndromes that Map to Chromosomal Regions Encoding TRP Channels -- TRP Channels of the Pancreatic Beta Cell -- TRP Channels in Platelet Function -- TRP Channels in Lymphocytes -- Link Between TRPV Channels and Mast Cell Function -- TRPV Channels' Role in Osmotransduction and Mechanotransduction -- Nociception and TRP Channels -- TRP Proteins -- Integrators of Multiple Inputs -- Regulation of TRP Ion Channels by Phosphatidylinositol-4,5-Bisphosphate -- TRPC, cGMP-Dependent Protein Kinases and Cytosolic Ca2+ -- Trafficking of TRP Channels: Determinants of Channel Function -- TRPC Channels: Interacting Proteins -- TRPC Channels: Integrators of Multiple Cellular Signals -- Phospholipase C-Coupled Receptors and Activation of TRPC Channels -- Erratum -- Erratum
Summary In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field have written 35 essays which describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs, from pharmacologists and physiologists to medical doctors, other scientists, students and lecturers. It fills a gap between pharmacology textbooks and latest manuscripts in scientific periodicals
Analysis fysiologie
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Print version record
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
In Springer e-books
Subject TRP channels.
Transient Receptor Potential Channels -- physiology
Transient Receptor Potential Channels
Mammalia (class)
SCIENCE -- Life Sciences -- Biochemistry.
Transient Receptor Potential Channels -- physiology.
TRP channels.
Sciences de la vie.
TRP channels
Form Electronic book
Author Abramowitz, J.
Flockerzi, Veit.
Nilius, B.
ISBN 9783540348917