| Description |
1 online resource |
| Series |
Subcellular biochemistry ; v. 52 |
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Sub-cellular biochemistry ; v. 52.
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| Contents |
Introduction to "a handbook of transcription factors" / T.R. Hughes -- An overview of prokaryotic transcription factors : a summary of function and occurrence in bacterial genomes / A.S. Seshasayee, K. Sivaraman and N.M. Luscombe -- A catalogue of eukaryotic transcription factor types, their evolutionary origin, and species distribution / M.T. Weirauch and T.R. Hughes -- Function and evolution of C2H2 zinc finger arrays / L. Stubbs, Y. Sun and D. Caetano-Anolles -- Homeodomain subtypes and functional diversity / T.R. Burglin -- Nuclear receptors : Small molecule sensors that coordinate growth, metabolism and reproduction / K. Pardee, A.S. Necakov and H. Krause -- Methods for analysis of transcription factor DNA-binding specificity in vitro / A. Jolma and J. Taipale -- Identification of transcription factor-DNA interactions in vivo / D.T. Odom -- How transcription factors identify regulatory sites in genomic sequence / Y. Field, E. Sharon and E. Segal -- Transcription factor binding sites and other features in human and Drosophila proximal promoters / C. Vinson, R. Chatterjee and P. Fitzgerald -- Interactions of transcription factors with chromatin / H. van Bakel -- Transcription factor effector domains / S. Frietze and P.J. Farnham -- Large-scale nuclear architecture and transcriptional control / J.M. Vaquerizas, A. Akhtar and N.M. Luscombe |
| Summary |
Transcription factors are - in the most common use of the term - proteins that possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes in proximity to the binding site. Transcription factors are the primary interface between the cell and the genome, and in aggregate control not only regulation of transcription but also genome organization, and play a central role in many aspects of physiology and evolution. This book will provide a reference for the major aspects of transcription factor biochemistry, function, and evolution. Contents will range from a general catalogue of known transcription factor classes, origins and evolution of transcription factor types, and mechanisms of interaction with chromatin, the nuclear scaffold, and RNA polymerase |
| Analysis |
biochemie |
|
biochemistry |
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nucleic acids |
|
chemie |
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chemistry |
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celbiologie |
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cellular biology |
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biomedische wetenschappen |
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biomedicine |
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Medicine (General) |
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Geneeskunde (algemeen) |
| Notes |
Print version record |
| Subject |
Transcription factors.
|
|
Transcription Factors -- genetics
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Transcription Factors -- physiology
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Transcription Factors
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Transcription factors
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| Form |
Electronic book
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| Author |
Hughes, T. R. (Timothy R.)
|
| ISBN |
9789048190690 |
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904819069X |
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