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Title Genome editing and engineering : from TALENs, ZFNs and CRISPRs to molecular surgery / edited by Krishnarao Appasani ; with a foreword by George M. Church
Published Cambridge : Cambridge University Press, 2018


Description 1 online resource (xxix, 472 pages) : PDF file(s)
Summary Recent advances in genome editing tools using endonucleases such as TALENs, ZFNs, and CRISPRs, combined with genomic engineering technologies, have opened up a wide range of opportunities from applications in the basic sciences and disease biology research, to the potential for clinical applications and the development of new diagnostic tools. This complete guide to endonuclease-based genomic engineering gives readers a thorough understanding of this rapidly expanding field. Chapters cover the discovery, basic science, and application of these techniques, focusing particularly on their potential relevance to the treatment of cancer, and cardiovascular and immunological disease. The final section discusses the legal and ethical issues which accompany the technology. Providing authoritative coverage of the potential that genome editing and engineering have, this is an ideal reference for researchers and graduate students and those working in the biotechnology and pharmaceutical industries, as well as in a clinical setting
Notes Title from publisher's bibliographic system (viewed on 01 Aug 2018)
Bibliography Includes bibliographical references
Notes Description based on online resource; title from digital title page (viewed on October 23, 2018)
Subject Genetics -- Computer simulation
Genetic engineering.
Gene editing.
Zinc-finger proteins.
CRISPR (Genetics)
Gene Editing
Transcription Activator-Like Effector Nucleases
Zinc Fingers
Clustered Regularly Interspaced Short Palindromic Repeats
Zinc-finger proteins
Gene editing
Genetic engineering
Genetics -- Computer simulation
Genre/Form Electronic books
Form Electronic book
Author Appasani, Krishnarao, 1959- editor.
ISBN 9781316756300