| Description |
1 online resource (396 pages) |
| Contents |
""Toxicity Testing""; ""Copyright""; ""PREFACE""; ""ACKNOWLEDGMENTS""; ""Contents""; ""EXECUTIVE SUMMARY""; ""SELECT UNIVERSE OF SUBSTANCES""; ""CHARACTERIZING TOXICITY-TESTING NEEDS""; ""QUANTITY AND NATURE OF TESTING""; ""QUALITY OF TESTING""; ""TOXICITY-TESTING NEEDS""; ""HEALTH-HAZARD ASSESSMENT""; ""INTERPRETATION OF PHYSICOCHEMICAL AND EXPOSURE DATA""; ""APPROACHES TO PRIORITY-SETTING""; ""INTRODUCTION""; ""THE NATIONAL TOXICOLOGY PROGRAM""; ""THE STUDY""; ""REFERENCES""; ""PART 1 TOXICITY-TESTING NEEDS IN THE SELECT UNIVERSE ""; ""Contents""; ""1 Introduction "" |
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""2 Sample Selection """"THE UNIVERSE AND THE SAMPLING FRAME""; ""Pesticides and Inert Ingredients of Pesticide Formulations""; ""Cosmetic Ingredients""; ""Drugs and Excipients in Drug Formulations""; ""Food Additives""; ""Chemicals in Commerce""; ""CONSIDERATIONS IN DEVELOPING THE SAMPLING STRATEGY""; ""SAMPLING STRATEGY""; ""Sample Size""; ""Sampling Plan""; ""SCREENING THE SAMPLE FOR MINIMAL TOXICITY INFORMATION""; ""3 Operating Policies for Identification, Acquisition, and Organization of Data ""; ""RESTRICTED-ACCESS OR CONFIDENTIAL INFORMATION""; ""INFORMATION ON TOXICITY IN HUMANS"" |
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""CHEMICAL AND PHYSICAL CHARACTERISTICS, MANUFACTURING PROCESSES, PRODUCTION VOLUMES, INTENDED USES AND�""""CHEMICAL REVIEW ARTICLES""; ""ARTICLES IN FOREIGN LANGUAGES""; ""SUBSTANCES STRUCTURALLY SIMILAR TO THOSE IN THE SAMPLE""; ""4 Data Evaluation ""; ""THE DOSSIER CONCEPT""; ""GENERAL PRINCIPLES FOR EVALUATION OF TOXICITY-TESTING PROTOCOLS""; ""CONSIDERATION OF EXPOSURE""; ""PURITY OF SELECTED SUBSTANCES""; ""GUIDELINES FOR ASSESSING THE QUALITY OF INDIVIDUAL STUDIES""; ""Basic Criteria for Scientific Methods""; ""Selection of Reference Protocols"" |
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""Reference Protocol Guidelines for Neurobehavioral-Toxicity Tests""""Reference Protocol Guidelines for Genetic-Toxicity Tests""; ""PROCEDURES FOR EVALUATION OF THE DATA BASE""; ""Initial Considerations""; ""Adequacy Ratings""; ""Measures of Adequacy for Tests Not Meeting the Reference Protocol Guidelines""; ""Dossier Review Process""; ""LIMITATIONS OF THE DATA GATHERING PROCESS""; ""INTERPRETATION OF DATA ON TESTING QUALITY""; ""CHARACTERIZING THE SAMPLE AND OPTIONS FOR DRAWING INFERENCES TO THE SELECT UNIVERSE""; ""Construction of Tables for Analysis""; ""Statistical Analysis of Data"" |
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""Estimates Based on the Sample Alone""""Estimates Based on the Subsample Alone""; ""Estimates Based on Both the Sample and the Subsample""; ""MACHINE-READABLE FILES""; ""5 Results ""; ""QUANTITY AND NATURE OF TESTING""; ""Sample of 675 Substances""; ""Subsample of 100 Substances""; ""QUALITY OF TESTING""; ""TESTING NEEDS""; ""HEALTH-HAZARD ASSESSMENT""; ""INTERPRETATION AND ANALYSIS OF PHYSICOCHEMICAL AND EXPOSURE DATA""; ""6 Summary and Conclusions ""; ""REFERENCES""; ""Appendix A Sample of 675 Substances and Subsample of 100 Substances from the ''Select Universe'' "" |
| Notes |
""Appendix B Testing for Various Situations of Chemical Use and General Exposure to Direct and Indirect and Indirect Food�"" |
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Print version record |
| Subject |
National Toxicology Program (U.S.)
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| SUBJECT |
National Toxicology Program (U.S.) fast |
| Subject |
Toxicity testing.
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Toxicity testing -- United States
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Toxicity testing
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United States
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| Form |
Electronic book
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| ISBN |
9780309554480 |
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0309554489 |
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