| Description |
1 online resource (312 pages) : illustrations |
| Contents |
Effects of chemicals -- Toxicokinetics -- Risk assessment and regulatory toxicology -- Descriptive animal toxicology tests -- Acute toxicology testing -- Subchronic and chronic toxicology testing -- Acute dermal and ocular toxicity testing -- Toxicity testing for fertility and reproduction -- Carcinogenicity and mutagenicity testing in vivo -- Toxicology testing in vitro -- Cell culture methodology -- Cell culture methods for acute toxicology testing -- Toxicokinetic studies in vitro -- Mutagenicity testing in vitro -- Reproductive and teratogenicity studies in vitro -- High throughput screening and microarray analysis -- Experimental design and statistics -- Standardization and validation of alternative methods -- Applications of alternative models for toxicology testing |
| Summary |
Providing comprehensive coverage of methods and important issues in toxicology testing, this book begins with an introduction to the fundamental basics of toxicology, including principles of toxicokinetics, adsorption, distribution, metabolism, and the elimination of xenobiotics. It presents a detailed discussion of toxicity testing in animals and addresses contemporary issues such as high throughput screening, risk analysis, standardization, and validation. With drawings, figures, tables, and charts to facilitate understanding, this text also features a unique chapter on the interpretation of the significance of toxicity testing results with an examination of the ultimate purpose of testing |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Toxicity testing.
|
|
Toxicity Tests -- methods
|
|
Toxicology -- methods
|
|
Toxicity Tests
|
|
Pharmacology, Clinical -- methods
|
|
Toxicity Tests -- standards
|
|
MEDICAL -- Toxicology.
|
|
Toxicity testing
|
| Form |
Electronic book
|
| ISBN |
9781420008326 |
|
1420008323 |
|
1281122602 |
|
9781281122605 |
|
